General
Preferred name
Alpha-Linolenic Acid
Synonyms
LINOLENIC ACID ()
α-Linolenic acid ()
¦Á-Linolenic acid ()
.alpha.-Linolenic Acid ()
.alpha.-Linolenic Acid-d14 ()
.alpha.-Linolenic Acid-d5 ()
?-Linolenic Acid (sodium salt) ()
α-linolenic acid ()
?-Linolenic Acid MaxSpec® Standard ()
??-Linolenic acid ()
P&D ID
PD010226
CAS
463-40-1
1622944-40-4
145191-04-4
822-18-4
Tags
available
drug
Approved by
FDA
Drug indication
Discovery agent
Drug Status
approved
investigational
nutraceutical
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
¦Á-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. ¦Á-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. ¦Á-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].
PRICE
29
DESCRIPTION
??-Linolenic Acid (ALA) is an essential fatty acid that cannot be synthesized by the human body and is obtained by isolating it from seed oils. ??-Linolenic acid has been shown to improve memory, inhibit thrombosis, and lower blood lipids.
DESCRIPTION
Linolenic acid is a polyunsaturated omega-3 fatty acid found in many supplements.
(Enamine Bioactive Compounds)
DESCRIPTION
α-Linolenic Acid (ALA) is an essential fatty acid that cannot be synthesized by the human body and is obtained by isolating it from seed oils. α-Linolenic acid has been shown to improve memory, inhibit thrombosis, and lower blood lipids.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
19
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Enamine Bioactive Compounds
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NURSA ligand set
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
72
Molecular Weight
278.22
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
13
Ring Count
0
Aromatic Ring Count
0
cLogP
5.66
TPSA
37.3
Fraction CSP3
0.61
Chiral centers
0.0
Largest ring
0.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Akt
PI3K
ELOVL4, FADS1, FADS2, FFAR1, FFAR4, PTGS2, SLC8A1, TRPV1
Akt,PI3K
MOA
omega 3 fatty acid stimulant
Pathway
Cytoskeletal Signaling
PI3K/Akt/mTOR signaling
PI3K/Akt/mTOR
Source data
