General
Preferred name
CIDOFOVIR
Synonyms
Cidofovir (dihydrate) ()
HPMPC dihydrate ()
(S)-HPMPC dihydrate ()
(S)-HPMPC ()
HPMPC ()
GS 0504 ()
Cidofovir (Vistide) ()
CIDOFOVIR ANHYDROUS ()
Cidofovir hydrate ()
HPMPC,Vistide,GS 0504 ()
Vistide ()
Anhydrous cidofovir ()
GS-0504 ()
NSC-742135 ()
Cidofovir dihydrate ()
P&D ID
PD010222
CAS
113852-37-2
149394-66-1
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
1996
Drug Status
approved
withdrawn
Drug indication
Cytomegalovirus infection
Antiviral
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
7
Organisms
23
Compound Sets
18
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
279.06
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
4
Rotatable Bonds
6
Ring Count
1
Aromatic Ring Count
1
cLogP
-1.66
TPSA
147.9
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
CMV
DNA/RNA Synthesis
Endogenous Metabolite
Orthopoxvirus
CMV,DNA/RNA Synthesis
Pathway
Anti-infection
DNA Damage/DNA Repair
Apoptosis
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
MOA
DNA/RNA Synthesis inhibitor
DNA polymerase inhibitor
Indication
acquired immunodeficiency syndrome (AIDS), cytomegalovirus retinitis
ATC
J05AB12
Therapeutic Class
Anti-HIV Agents
Source data
