General
Preferred name
DYDROGESTERONE
Synonyms
NSC 92336 ()
Gynorest ()
Duphaston ()
Duphaston-Hrt ()
NSC-92336 ()
Isopregnenone ()
P&D ID
PD010215
CAS
152-62-5
Tags
natural product
drug
available
Approved by
PMDA
FDA
First approval
1982
1965
Drug Status
investigational
approved
withdrawn
Drug indication
Progestin
Menstrual disorder
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Dydrogesterone is a synthetic progestogen with no androgenic or estrogenic properties which unusually does not inhibit ovulation.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
312.21
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
0
cLogP
4.5
TPSA
34.14
Fraction CSP3
0.71
Chiral centers
6.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
infertility
Target
PGR
Progesterone Receptor
Estrogen/progestogen Receptor
MOA
Progesterone receptor agonist
ATC
G03DB01
Therapeutic Class
Progesterones
Pathway
Vitamin D Related/Nuclear Receptor
Source data