General
Preferred name
DYDROGESTERONE
Synonyms
NSC 92336 ()
Gynorest ()
Duphaston ()
Duphaston-Hrt ()
NSC-92336 ()
Isopregnenone ()
P&D ID
PD010215
CAS
152-62-5
Tags
natural product
drug
available
Approved by
PMDA
FDA
First approval
1982
1965
Drug Status
investigational
approved
withdrawn
Drug indication
Progestin
Menstrual disorder
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dydrogesterone is a synthetic progestogen with no androgenic or estrogenic properties which unusually does not inhibit ovulation. (GtoPdb)
Compound Sets
17
Cayman Chemical Bioactives
20514
ChEMBL Approved Drugs
CHEMBL1200853
ChEMBL Drugs
CHEMBL1200853
Drug Repurposing Hub
DrugBank
DB00378
DrugBank Approved Drugs
DB00378
DrugCentral
975
DrugCentral Approved Drugs
975
DrugMAP
DMAKIDV
DrugMAP Approved Drugs
DMAKIDV
EU-OPENSCREEN Bioactive Compound Library
EOS101687
Guide to Pharmacology
2878
MedChem Express Bioactive Compound Library
HY-B0257A
NPC Screening Collection
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
dydrogesterone
Withdrawn 2.0
DB00378
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
312.21
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
0
cLogP
4.5
TPSA
34.14
Fraction CSP3
0.71
Chiral centers
6.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
infertility
Target
PGR
Progesterone Receptor
Estrogen/progestogen Receptor
MOA
Progesterone receptor agonist
ATC
G03DB01
Therapeutic Class
Progesterones
Pathway
Vitamin D Related/Nuclear Receptor
Source data