General
Preferred name
CYSTINE
Synonyms
Cystine Acid ()
L-Cystine (dihydrochloride) ()
L-cystine ()
L-Cystine (hydrochloride) ()
L-Cystine dihydrochloride ()
Cistina ()
Cystine, l- ()
NSC-13203 ()
Cystine dihydrochloride ()
P&D ID
PD010209
CAS
349-46-2
56-89-3
30925-07-6
34760-60-6
Tags
available
drug
Drug Status
approved
investigational
nutraceutical
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
L-Cystine dihydrochloride is the dihydrochloride salt form of L-Cystine (HY-N0394). L-Cystine dihydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine dihydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine dihydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine dihydrochloride is promising for research of cystinuria and kidney stones[1][2][3][4][5][6]
PRICE
29
DESCRIPTION
L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cysteine amino acid thiol side chains. It functions as an antioxidant and protects tissues against radiation and pollution, slowing the aging process. It also aids protein synthesis. L-Cystine (Cystine Acid) is abundant in many proteins of skeletal tissues and skin, and found in insulin and digestive enzymes chromotrypsinogen A, papain, and trypsinogen.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Cystine is an oxidated derivative of the amino acid cysteine found in various nutritional products, acne treatments, and creams to treat cervical injury or inflammation. Cystine serves as a major precursor for synthesis of glutathione.
(Enamine Bioactive Compounds)
DESCRIPTION
L-Cystine dihydrochloride is an Nrf2 inducer with whitening and anti-dark spot effects.L-Cystine dihydrochloride has cytoprotective effects in cells, and is often added to various fungal cultures as a carbon source.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Enamine Bioactive Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
65
Molecular Weight
240.02
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
7
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.81
TPSA
126.64
Fraction CSP3
0.67
Chiral centers
2.0
Largest ring
0.0
QED
0.34
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antioxidant
Endogenous Metabolite
Ferroptosis
Nrf2
CTNS, SLC3A1, SLC7A11, SLC7A9
Apoptosis
Keap1-Nrf2
Reactive Oxygen Species (ROS)
ROS Kinase
Reactive Oxygen Species
Pathway
Metabolism
oxidation-reduction
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
Protein Tyrosine Kinase/RTK
NF-¦ÊB
Source data
