General
Preferred name
riboflavin
Synonyms
VITAMIN B2 ()
E101 ()
Freeda ()
Russupteridine yellow iii ()
NSC-33298 ()
Bisulase ()
INS NO. 101(I) ()
Riboflavina ()
Vitamin-b2 ()
C.i. food yellow 15 ()
Vitamin B 2 ()
E-101(iii) ()
Riboflavin component of vitaped ()
Vitamin b-2 ()
Ins no.101(iii) ()
Riboflavine ()
NCI-0033298 ()
Lacto-flavin ()
Riboflavin (vit b2) ()
C.i. 50900 ()
Vitamin b2 (as riboflavin) ()
Ins-101(iii) ()
Riboflavinum ()
E-B2 ()
Riboflavin-d7 ()
P&D ID
PD010207
CAS
83-88-5
Tags
available
drug
Approved by
FDA
First approval
1993
1953
Drug indication
psoriasis
Acne vulgaris
Drug Status
vet_approved
approved
investigational
nutraceutical
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Riboflavin (vitamin B2) is a water-soluble vitamin that is required for the biosynthesis of flavin-derived enzyme cofactors that are essential for cellular respiration. Taken as a dietary supplement to combat vitamin B2 deficiency.
(GtoPdb)
DESCRIPTION
Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction[1].
DESCRIPTION
Riboflavin is a vitamin used to correct vitamin B2 deficiency. It binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
20
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine Bioactive Compounds
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
48
Molecular Weight
376.14
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
5
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
1
cLogP
-1.72
TPSA
161.56
Fraction CSP3
0.41
Chiral centers
3.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
BLVRB, RFK
Bacterial
Endogenous Metabolite
Indication
jaundice
MOA
vitamin B
Pathway
Anti-infection
Metabolic Enzyme/Protease
Source data
