General
Preferred name
N-ACETYLGLUCOSAMINE
Synonyms
NAG ()
N-Acetyl-2-amino-2-deoxyglucose ()
Marine Sweet ()
N-Acetyl-2-amino-2-deoxy-D-glucose ()
GlcNAc ()
ART-144 ()
N-acetyl-D-Glucosamine ()
P&D ID
PD010206
CAS
7512-17-6
Tags
available
drug
Drug Status
approved
investigational
nutraceutical
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits[1][2][3].
PRICE 29
DESCRIPTION N-Acetyl-D-Glucosamine (NAG) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. (TargetMol Bioactive Compound Library)
Compound Sets
8
Cayman Chemical Bioactives
13136
Drug Repurposing Hub
DrugBank
DB00141
DrugBank Approved Drugs
DB00141
MedChem Express Bioactive Compound Library
HY-A0132
ReFrame library
Selleckchem Bioactive Compound Library
n-acetylglucosamine
TargetMol Bioactive Compound Library
T4514
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
221.09
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
5
Rotatable Bonds
6
Ring Count
0
Aromatic Ring Count
0
cLogP
-3.23
TPSA
127.09
Fraction CSP3
0.75
Chiral centers
4.0
Largest ring
0.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Human Endogenous Metabolite
B4GALT1, B4GALT2, B4GALT3, B4GALT4, NAGK, NAGLU, NAGPA, RENBP
Drug Derivative
Drug isomer
Interleukin Related
Pathway
Metabolism
Immunology/Inflammation
Metabolic Enzyme/Protease
Source data