General
Preferred name
PYRIDOXINE
Synonyms
PYRIDOXINE HYDROCHLORIDE ()
Pyridofylline ()
pyridoxine-pyrrolidone carboxylat ()
Metasin ()
Metadoxil ()
Pyridoxol ()
Vitamin B6 ()
Gravidox ()
Pyridoxine HCl ()
Pyridoxol (hydrochloride) ()
Vitamin B6 (hydrochloride) ()
Vitamin B6 (hydrochloride)Pyridoxol (hydrochloride)Pyridoxine HCl ()
Metadoxine ()
Pyridoxine pyrolate ()
Pyridoxine (hydrochloride) ()
Vitamin B6,Pyridoxol hydrochloride ()
Pyridoxol, Vitamin B6, Gravidox ()
Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat ()
Hexa-Betalin ()
Pyridoxini hydrochloridum ()
Pyridoxol hydrochloride ()
Vitalife ()
Pyridoxine hydrochloride component of bendectin ()
Lyphomed ()
Pyridoxine hydrochloride component of bonjesta ()
Pyridoxinum hydrochloricum ()
Pyridoxine hydrochloride component of diclegis ()
Vital Foods ()
Pyrid-10 ()
Pyridoxine hydrochloride component of tpn ()
Vitamin B6 Hydrochloride ()
Pyridox-Roche ()
Pyridoxine hydrochloride component of diclectin ()
Benadon ()
Pyridoxine chloride ()
Kent B6 ()
NSC-36225 ()
Pyrid-20 ()
Pyridox HCl ()
Comploment Continus ()
Orovite Comploment B6 ()
Hexabione ()
NSC-759148 ()
Adermine ()
Piridoxina ()
Pyridoxine (vit b6) ()
Pyridoxine component of vitaped ()
Vitamin v6 ()
M.V.I.-12 ()
Vitamin b-6 ()
Pyridoxine-d3 (hydrochloride) ()
P&D ID
PD010192
CAS
8059-24-3
8064-77-5
58-56-0
85153-84-0
74536-44-0
65-23-6
1189921-12-7
Tags
available
drug
Approved by
FDA
First approval
1993
1982
Drug indication
Movement disorder
Vitamin B6 deficiency
Iron deficiency anemia
Multiple myeloma
Drug Status
investigational
experimental
vet_approved
approved
nutraceutical
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
PRICE 29
DESCRIPTION Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
PRICE 29
PRICE 29
DESCRIPTION Pyridoxine hydrochloride (Vitamin B6) is the 4-methanol form of vitaminB6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. (TargetMol Bioactive Compound Library)
DESCRIPTION Pyridoxine is a 4-methanol form of vitamin B6 that is converted to pyridoxal 5’-phosphate, the active form of vitamin B6 and an important cofactor for metabolism. It has been used in cell culture media as a precursor to pyridoxal 5’-phosphate. Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of Isoniazid-induced peripheral neuropathy. (Enamine Bioactive Compounds)
DESCRIPTION Pyridoxine (Vitamin B6) is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Although pyridoxine and vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading. (TargetMol Bioactive Compound Library)
DESCRIPTION Metadoxine (Metadoxil) is a neurotransmitter stimulant. (TargetMol Bioactive Compound Library)
Compound Sets
23
AdooQ Bioactive Compound Library
A11910
Cayman Chemical Bioactives
20706
28149
ChEMBL Approved Drugs
CHEMBL1200756
CHEMBL1364
ChEMBL Drugs
CHEMBL1200756
CHEMBL1364
Drug Repurposing Hub
DrugBank
DB00165
DB16554
DrugBank Approved Drugs
DB00165
DrugCentral
2836
DrugCentral Approved Drugs
2836
DrugMAP
DMDBZMV
DMM4QOJ
DrugMAP Approved Drugs
DMDBZMV
DMM4QOJ
DrugMatrix
Enamine Bioactive Compounds
EBC-04089
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-N0682
HY-B1328
HY-B1898
NCATS Inxight Approved Drugs
KV2JZ1BI6Z
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
pyridoxine-hydrochloride
pyridoxine
metadoxine
TargetMol Bioactive Compound Library
T0973L
T0973
T3269
The Spectrum Collection
External IDs
96
Properties
(calculated by RDKit )
Molecular Weight
169.07
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.08
TPSA
73.58
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.59
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
NF-??
GPCR/G protein
Neuroscience
Tyrosine Kinase/Adaptors
Cell Cycle/Checkpoint
Immunology/Inflammation
Metabolism
Metabolic Enzyme/Protease
NF-κB
Stem Cell/Wnt
TGF-beta/Smad
Target
5-HT2B
PKA
Endogenous Metabolite
Keap1-Nrf2
PLK
VB6
DDC, PDXK
Vitamin
5-HT Receptor
Indication
vitamin B6 deficiency
MOA
vitamin B
Therapeutic Class
Vitamins
Source data