General
Preferred name
ADENOSINE TRIPHOSPHATE
Synonyms
Ara-ATP ()
Atipi ()
ATP ()
Triphosphaden ()
Triphosphoric acid adenosine ester ()
ATP disodium salt hydrate ()
ATP disodium salt ()
Disodium adenosine triphosphate ()
adenosine-triphosphate ()
ATP disodium ()
Adetide ()
Adenosine 5'-triphosphate disodium salt ()
ATP (Adenosine-Triphosphate) ()
AMPPCP ()
ADENOSINE TRIPHOSPHATE DISODIUM ()
Adenosine disodium triphosphate hydrate ()
Adenosine-Triphosphate disodium, ATP disodium salt, Adenosine 5'-triphosphate ()
Adenosine-Triphosphate, Adenosine 5'-triphosphate ()
NSC-20268 ()
Adenosine 5'-triphosphoric acid ()
Adenosine 5'-triphosphate (sodium salt) ()
Adenosine 5'-triphosphate (sodium salt) (solution) ()
P&D ID
PD010189
CAS
56-65-5
987-65-5
56560-86-2
10168-83-9
34369-07-8
Tags
drug candidate
natural product
drug
available
Drug indication
Heart disease
Malnutrition
Bradycardia
Drug Status
nutraceutical
investigational
approved
Max Phase
Phase 2
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Potent and highly selective group II mGlu agonist (Tocris Bioactive Compound Library)
Compound Sets
22
AdooQ Bioactive Compound Library
A11672
Cayman Chemical Bioactives
14498
40182
ChEMBL Drugs
CHEMBL2106579
CHEMBL14249
Concise Guide to Pharmacology 2017/18
1713
Concise Guide to Pharmacology 2019/20
1713
Concise Guide to Pharmacology 2021/22
1713
Concise Guide to Pharmacology 2023/24
1713
Drug Repurposing Hub
DrugBank
DB00171
DrugCentral
91
DrugCentral Approved Drugs
91
DrugMAP
DM79F6G
DrugMAP Approved Drugs
DM79F6G
EU-OPENSCREEN Bioactive Compound Library
EOS100983
Guide to Pharmacology
1713
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL14249
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
atp-Adenosine-Triphosphate
atp
adenosine-disodium-triphosphate
TargetMol Bioactive Compound Library
T1352
T20089
Tocris Bioactive Compound Library
3245
ZINC Tool Compounds
ZINC000004261765
External IDs
117
Properties
(calculated by RDKit )
Molecular Weight
507.0
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
7
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.63
TPSA
279.13
Fraction CSP3
0.5
Chiral centers
6.0
Largest ring
6.0
QED
0.2
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Membrane Transporter/Ion Channel
Target
Endogenous Metabolite
P2X Receptor
ABCA1, ABCB1, ABCB11, ABCC2, ABCC8, ABCC9, ABCG1, ABL1, ABL2, ACSL1, ACSS1, ACSS2, ACVR1, ACVR1B, ACVRL1, ADCY1, ADRBK1, ADRBK2, AFG3L2, AKT1, ALK, AMHR2, APAF1, ARAF, ASNA1, ASNS, ASS1, CDK15, GPR17, ITPR1, NAE1, NT5C2, P2RY1, P2RY11, P2RY13, P2RY2, P2RY4, PRKAA1, RYR1, RYR2, RYR3, SLC25A4, TNK2, TRPM4, TRPM7
Immunology & Inflammation related
Primary Target
Purinergic (P2Y) Receptors
MOA
Agonist
Adenosine Receptor agonist
Therapeutic Class
Dietary supplement
Source data