General
Preferred name
BETAXOLOL
Synonyms
BETAXALOL HYDROCHLORIDE ()
BETAXOLOL HYDROCHLORIDE ()
levobetaxolol ()
Betaxolol HCl ()
SL 75212 HCl ()
KERLONE ()
SL 75212 ()
BETOPTIC ()
Betaxolol (hydrochloride) ()
SL75212 ()
SL 75212,Dextrobetaxolol ()
BETOPTIC S ()
Betaxolol hydrochloride component of kerledex ()
SL-75.212-10 ()
SL-75212-10 ()
NSC-760048 ()
SL-7521210 ()
ALO 1401-02 ()
SL 75.212-10 ()
Betaxolol hydrochloride component of betoptic pilo ()
ALO-140102 ()
ALO-1401-02 ()
SL-7521210 FREE BASE ()
Betoptic Susp ()
ALO-140102 FREE BASE ()
Kerledex ()
Betaxolol ()
BETAXOLOL HYDROCHLORIDE COMPONENT OF BETOPTIC PILO ()
BETAXOLOL HYDROCHLORIDE COMPONENT OF KERLEDEX ()
Betaxolol-d7 (hydrochloride) ()
P&D ID
PD010175
CAS
63659-18-7
72424-72-7
63659-19-8
1219802-92-2
Tags
available
drug
Approved by
FDA
First approval
1985
Drug indication
Hypertension
Cardiovascular disease
Open-angle glaucoma
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.
PRICE
29
DESCRIPTION
Betaxolol is a cardioselective β1-adrenoceptor antagonist.
(GtoPdb)
DESCRIPTION
Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.
PRICE
33
DESCRIPTION
Selective 5-HT2A antagonist. Also antagonist at 5-HT1D
(Tocris Bioactive Compound Library)
DESCRIPTION
Selective beta1 adrenoceptor antagonist
(LOPAC library)
DESCRIPTION
Selective β1 antagonist
(Tocriscreen Total)
DESCRIPTION
Betaxolol hydrochloride (SL 75212 HCl) is a cardioselective beta-blocker used in the treatment of hypertension.Betaxolol hydrochloride has not been linked to instances of clinically apparent drug induced liver injury.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
31
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EUbOPEN Chemogenomics Library
Guide to Pharmacology
Ki Database
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
65
Molecular Weight
307.21
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
11
Ring Count
2
Aromatic Ring Count
1
cLogP
2.39
TPSA
50.72
Fraction CSP3
0.67
Chiral centers
1.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
beta1
Target
Adrenergic Receptor
β1-adrenergic receptor
Primary Target
Adrenergic ?1 Receptors
MOA
Antagonist
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Therapeutic Class
Antihypertensive Agents
Recommended Cell Concentration
100 nM
Source data
