General
Preferred name
succinylcholine
Synonyms
Suxamethonium chloride ()
SUCCINYLCHOLINE CHLORIDE ()
Suxamethonium Chloride Dihydrate ()
choline chloride succinate ()
Succinyldicholine dichloride ()
Succinylcholine Chloride Dihydrate ()
SUXAMETHONIUM ()
SUXAMETHONIUM BROMIDE ()
Suxamethonium cation ()
Succinylcholine ()
Succinylcholine ion ()
Suxamethonium ion ()
Sucostrin ()
Succinylcholine cation ()
Anectine ()
Quelicin ()
Choline chloride succinate (2:1) ()
NSC-49132 ()
Suxamethonii chloridum ()
Suxamethonium chloride dihydrate ()
Scoline ()
Suxamethonium Chloride ()
Suxamethonium chloride hydrate ()
Quelicin Preservative Free ()
Suxamethone ()
Succinylcholine bromide ()
NSC-151059 ()
Succinylcholine (chloride hydrate) ()
P&D ID
PD010173
CAS
6101-15-1
306-40-1
10168-63-5
71-27-2
Tags
available
drug candidate
drug
Approved by
FDA
First approval
1952
Drug Status
approved
Drug indication
Spasm
Neuromuscular Blocking Agent
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Succinylcholine (sux) is a short-acting depolarizing neuromuscular blocker. It acts as an acetylcholine agonist at nicotinic acetylcholine receptors at neuromuscular junctions, resulting in persistent depolarization of the motor end plate. (GtoPdb)
DESCRIPTION Nicotinic acetylcholine receptor antagonist. (LOPAC library)
DESCRIPTION Succinylcholine Chloride Dihydrate is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker. (BOC Sciences Bioactive Compounds)
Cell lines
1
Organisms
0
Compound Sets
25
BOC Sciences Bioactive Compounds
succinylcholine-chloride-dihydrate-cas-6101-15-1-item-84-129284
Cayman Chemical Bioactives
32829
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL703
CHEMBL983
ChEMBL Drugs
CHEMBL703
CHEMBL983
CHEMBL2104486
Concise Guide to Pharmacology 2017/18
4004
Concise Guide to Pharmacology 2019/20
4004
Concise Guide to Pharmacology 2021/22
4004
Concise Guide to Pharmacology 2023/24
4004
Drug Repurposing Hub
DrugBank
DB00202
DrugBank Approved Drugs
DB00202
DrugCentral
2489
DrugCentral Approved Drugs
2489
DrugMAP
DM2ET1M
DrugMAP Approved Drugs
DM2ET1M
DrugMatrix
Guide to Pharmacology
4004
Ki Database
Succinylcholine
LOPAC library
NCATS Inxight Approved Drugs
J2R869A8YF
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
succinylcholine-suxamethonium-chloride-dihydrate
TargetMol Bioactive Compound Library
T6684
External IDs
76
Properties
(calculated by RDKit )
Molecular Weight
290.22
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
9
Ring Count
0
Aromatic Ring Count
0
cLogP
0.27
TPSA
52.6
Fraction CSP3
0.86
Chiral centers
0.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Nicotinic
MOA
nicotinic acetylcholine receptor antagonist
AChR agonist
Target
Muscle-type nicotinic acetylcholine receptor
Nicotinic AChR
CHRFAM7A, CHRM1, CHRM2, CHRM3, CHRNA1, CHRNA10
AChR
Pathway
Neuroscience
Indication
muscle relaxant
Therapeutic Class
Analgesics
Solubility
Soluble in DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)
Source data