General
Preferred name
succinylcholine
Synonyms
Suxamethonium chloride ()
SUCCINYLCHOLINE CHLORIDE ()
choline chloride succinate ()
Succinyldicholine dichloride ()
Suxamethonium Chloride Dihydrate ()
SUXAMETHONIUM ()
Succinylcholine Chloride Dihydrate ()
Trimethyl[2-({4-oxo-4-[2-(trimethylammonio)ethoxy]butanoyl}oxy)ethyl]ammonium ()
SUXAMETHONIUM BROMIDE ()
Succinylcholine ()
Succinylcholine cation ()
Succinylcholine ion ()
Suxamethonium ion ()
Suxamethonium cation ()
Scoline ()
Suxamethonium Chloride ()
NSC-49132 ()
Quelicin ()
Cloruro de suxametonio ()
Suxamethone ()
Suxamethonium chloride hydrate ()
Suxamethonium chloride dihydrate ()
Chlorure de suxamethonium ()
Anectine ()
Suxamethonii chloridum ()
Quelicin Preservative Free ()
Choline chloride succinate (2:1) ()
Sucostrin ()
Succinylcholine bromide ()
NSC-151059 ()
Succinylcholine (chloride hydrate) ()
P&D ID
PD010173
CAS
6101-15-1
306-40-1
10168-63-5
71-27-2
Tags
available
drug
drug candidate
Approved by
FDA
First approval
1952
Drug indication
Spasm
Stroke
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Succinylcholine (sux) is a short-acting depolarizing neuromuscular blocker. It acts as an acetylcholine agonist at nicotinic acetylcholine receptors at neuromuscular junctions, resulting in persistent depolarization of the motor end plate.
(GtoPdb)
DESCRIPTION
Succinylcholine Chloride Dihydrate is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Succinylcholine chloride is an agonist of muscle-type nicotinic acetylcholine receptors. Succinylcholine is a depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures.
(Enamine Bioactive Compounds)
DESCRIPTION
Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Nicotinic acetylcholine receptor antagonist.
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
27
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
CeMM library of unique drugs (CLOUD)
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Guide to Pharmacology
Ki Database
LOPAC library
NCATS Inxight Approved Drugs
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
83
Molecular Weight
290.22
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
9
Ring Count
0
Aromatic Ring Count
0
cLogP
0.27
TPSA
52.6
Fraction CSP3
0.86
Chiral centers
0.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Nicotinic
MOA
nicotinic acetylcholine receptor antagonist
AChR agonist
Target
Muscle-type nicotinic acetylcholine receptor
nAChR
CHRFAM7A, CHRM1, CHRM2, CHRM3, CHRNA1, CHRNA10
AChR
Indication
muscle relaxant
Pathway
Neuroscience
Therapeutic Class
Analgesics
Solubility
Soluble in DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)
Source data
