General
Preferred name
ENFLURANE
Synonyms
NSC115944 ()
Ethrane ()
NSC-115944 ()
Efrane ()
NSC 115944 ()
Enflurano ()
Alyrane ()
Anesthetic Compound No. 347 ()
Methylflurether ()
Ohio 347 ()
Compound 347 ()
R-E-235CA2 ()
P&D ID
PD010158
CAS
13838-16-9
Tags
available
drug
Approved by
FDA
First approval
1972
Drug indication
Anaesthesia
Drug Status
vet_approved
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Enflurane is a halogenated ether inhalational anaesthetic, but it is no longer in common use. It is a structural isomer of .
(GtoPdb)
DESCRIPTION
Enflurane is a halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery.
(Enamine Bioactive Compounds)
DESCRIPTION
Enflurane (Efrane), a volatile anaesthetic, is a potent inhibitor of high conductance Ca2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry. It allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
JUMP-Target 1 Compound Set
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Molecular Weight
183.97
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
2.35
TPSA
9.23
Fraction CSP3
1.0
Chiral centers
1.0
Largest ring
0.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ATP5F1D
Therapeutic Class
Anesthetics
Source data
