General
Preferred name
IDOXURIDINE
Synonyms
5-Iodo-2ยกรค-deoxyuridine ()
5-Iodo-2??-deoxyuridine ()
IDU ()
5-IUdR ()
NSC 39661 ()
SKF 14287 ()
Dendrid ()
5-Iodo-2??deoxyuridine ()
NSC 39661, SKF 14287,5-Iodo-2??-deoxyuridine,5-IUdR,IdUrd ()
ALLERGAN211 ()
Allergan 211 ()
5IUDR ()
Kerecid ()
5-IUDR ()
Herplex ()
Joddeoxiuridin ()
Allergan-211 ()
NSC-39661 ()
Stoxil ()
SK&F-14287 ()
Ophthalmadine ()
Idoxuridina ()
SK&F 14287 ()
Idoxuridinum ()
Idox ()
P&D ID
PD010145
CAS
54-42-2
1336-77-2
Tags
available
drug
probe
Approved by
FDA
First approval
1963
Drug indication
Herpes simplex virus infection
Antiviral (ophthalmic)
Drug Status
approved
investigational
Max Phase
4.0
Probe info
Probe type
calculated probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
5
Compound Sets
18
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
LSP-MoA library (Laboratory of Systems Pharmacology)
NPC Screening Collection
Prestwick Chemical Library
Probe Miner (suitable probes)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
353.97
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
-1.22
TPSA
104.55
Fraction CSP3
0.56
Chiral centers
3.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Target
Feline herpesvirus type-1(FHV-1)
Antiviral
MOA
DNA directed DNA polymerase inhibitor, DNA synthesis inhibitor
Indication
virus herpes simplex (HSV)
Therapeutic Class
Antiviral Agents
Source data
