General
Preferred name
ADINAZOLAM
Synonyms
adinazolam mesylate ()
U-41,123 ()
U-41123 ()
Adinazolam mesilate ()
U-41,123F ()
Adinazolam methanesulfonate ()
U-41123F ()
Adinazolam (CRM) ()
P&D ID
PD010139
CAS
37115-32-5
57938-82-6
Tags
available
drug
drug candidate
Drug indication
Anxiety disorder
Anxiety
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
METABOLISM The drug primarily undergoes hepatic metabolism to form the main metabolite N-desmethyladinazolam, alpha-hydroxyalprazolam, and estazolam.
DESCRIPTION Adinazolam is a triazolobenzodiazepine (TBZD). It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties. (TargetMol Bioactive Compound Library)
Compound Sets
13
Cayman Chemical Bioactives
18205
30186
ChEMBL Drugs
CHEMBL328250
CHEMBL2106672
DrugBank
DB00546
DrugCentral
93
DrugCentral Approved Drugs
93
DrugMAP
DMBHO9Y
DrugMAP Approved Drugs
DMBHO9Y
DrugMatrix
Ki Database
Adinazolam
Mcule NIBR MoA Box Subset
MCULE-9409005171
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
TargetMol Bioactive Compound Library
T8665
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
351.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
3.33
TPSA
46.31
Fraction CSP3
0.21
Chiral centers
0.0
Largest ring
7.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
Peripheral-type benzodiazepine receptors potentiator
Therapeutic Class
Antidepressants
Source data