General
Preferred name
Flucloxacillin
Synonyms
floxacillin sodium ()
FLOXACILLIN ()
Flucloxacillin sodium ()
FLUCOXACILLIN ()
Flucloxacillin Sodium ()
BRL-2039 ()
Abboflox ()
Floxapen ()
Floxacillin sodium anhydrous ()
Ladropen ()
Fluclomix-250 ()
Flucloxacillin sodium monohydrate ()
Stafoxil ()
Galfloxin ()
Flucloxacilline ()
NSC-277175 ()
Flucloxacillin sodium anhydrous ()
Fluclomix-500 ()
Flucloxin ()
Zoxin 500 ()
BRL 2039 ()
Rimaflox ()
Flucloxacilina ()
Culpen ()
Staphylex ()
Staphlipen ()
Zoxin 250 ()
Flucloxacillin (sodium salt) ()
P&D ID
PD010114
CAS
5250-39-5
1847-24-1
Tags
available
drug
First approval
1962
Drug indication
Chronic kidney disease
Bacterial infection
Drug Status
approved
investigational
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Flucloxacillin is a narrow-spectrum, semisynthetic penicillin (β-lactam) antibacterial. It is β-lactamase stable. (GtoPdb)
DESCRIPTION Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria[1][2].
PRICE 29
DESCRIPTION Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria. (TargetMol Bioactive Compound Library)
Compound Sets
16
Cayman Chemical Bioactives
35241
ChEMBL Drugs
CHEMBL222645
Drug Repurposing Hub
DrugBank
DB00301
DrugBank Approved Drugs
DB00301
DrugCentral
1183
DrugCentral Approved Drugs
1183
DrugMAP
DMNUWST
DrugMAP Approved Drugs
DMNUWST
Guide to Pharmacology
10910
MedChem Express Bioactive Compound Library
HY-A0246A
NPC Screening Collection
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
flucloxacillin-sodium
TargetMol Bioactive Compound Library
T5006
External IDs
52
Properties
(calculated by RDKit )
Molecular Weight
453.06
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
2.69
TPSA
112.74
Fraction CSP3
0.37
Chiral centers
3.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Antibiotics,Bacterial
MOA
Antibacterial
bacterial cell wall synthesis inhibitor
Indication
gram-positive bacterial infections, tonsillitis, sinusitis, pneumonia, eczema, endocarditis, meningitis, enteritis, bacterial septicemia
Disease Area
infectious disease, otolaryngology, dermatology, gastroenterology
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Antibiotics
Source data