General
Preferred name
ERTAPENEM
Synonyms
MK-826 ()
L-749345 ()
ERTAPENEM SODIUM ()
Invanz ()
Ertapenem (disodium) ()
MK-0826 (disodium) ()
MK826 ()
Ertapenem (sodium salt) ()
Ertapenem sodium salt ()
Ertapenem sun ()
MK-0826 ()
P&D ID
PD010113
CAS
153832-38-3
153832-46-3
153773-82-1
Tags
available
drug
Approved by
FDA
EMA
First approval
2001
Drug indication
gonorrhea
Urinary tract infection
Bacterial infection
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ertapenem (MK-0826) disodium is a broad spectrum and long acting ¦Â-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 ¦Ìg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].
DESCRIPTION
Ertapenem is a carbapenem and broad-spectrum β-lactam antibacterial.
(GtoPdb)
PRICE
53
DESCRIPTION
Ertapenem sodium (MK-826) is a new long-acting 1-??-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with extended-spectrum ??-lactamases.
DESCRIPTION
Ertapenem sodium (MK-826) is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
82
Molecular Weight
475.14
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
5
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
1
cLogP
0.94
TPSA
156.27
Fraction CSP3
0.45
Chiral centers
6.0
Largest ring
6.0
QED
0.36
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
MOA
Antibiotic
Biosynthetic Origin
Peptide (beta-Lactam)
Therapeutic Indication
Antibacterial
Therapeutic Class
Antimicrobial
Antibiotics
Pathway
Microbiology/virology
Anti-infection
Source data
