General
Preferred name
PENTOBARBITAL
Synonyms
PENTOBARBITAL SODIUM ()
Pentobarbital-d5 ()
Pentobarbital-d5 (CRM) ()
Pentobarbital (CRM) ()
pentobarbitone ()
Nembutal ()
Pentobarbital cii ()
NSC-28708 ()
Isobarb ()
Praecicalm ()
Sodium-pent ()
Etaminal sodium ()
Pentobarbitone Sodium ()
Barpental ()
Somnotol ()
Pacifan ()
Sodium ethaminal ()
Sodium pentobarbiturate ()
Pental ()
Mebumal sodium ()
Pentobarbital sodium salt ()
Ethaminal sodium ()
Sopental ()
NSC-10816 ()
Euthatal ()
Somnopentyl ()
Pentonal ()
Vetbutal ()
Sodium Pentobarbital ()
Euthanase ()
Embutal ()
Auropan ()
Sodium nembutal ()
V-pento ()
Sodium pental ()
Biosedan ()
Sodium pentobarbitone ()
Nembutal Sodium ()
Pentone ()
Rs-pentobarbital sodium ()
Diabutal ()
Soluble pentobarbital ()
Sagatal ()
Euthanyl ()
Napental ()
Narcoren ()
Mebubarbital sodium ()
Sotyl ()
Entobar ()
P&D ID
PD010108
CAS
76-74-4
57-33-0
10579-81-4
23714-57-0
52944-66-8
Tags
available
drug
Approved by
FDA
First approval
1973
Drug indication
Heart disease
Insomnia
Drug Status
vet_approved
approved
withdrawn
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pentobarbital is a racemic mixture of two enantiomers; (R)-pentobarbital and (S)-pentobarbital. (GtoPdb)
Cell lines
0
Organisms
1
Compound Sets
17
Cayman Chemical Bioactives
20965
20966
20968
20969
ChEMBL Approved Drugs
CHEMBL448
CHEMBL971
ChEMBL Drugs
CHEMBL448
CHEMBL971
DrugBank
DB00312
DrugBank Approved Drugs
DB00312
DrugCentral
2095
DrugCentral Approved Drugs
2095
DrugMAP
DMFNH7L
DrugMAP Approved Drugs
DMFNH7L
DrugMatrix
Guide to Pharmacology
5480
Ki Database
Pentobarbital
NCATS Inxight Approved Drugs
I4744080IR
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Withdrawn 2.0
w223
External IDs
69
Properties
(calculated by RDKit )
Molecular Weight
226.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
0
cLogP
1.18
TPSA
75.27
Fraction CSP3
0.73
Chiral centers
1.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N05CA01
Toxicity type
multiple
Therapeutic Class
Hypnotics and Sedatives
Source data