General
Preferred name
PIPERACILLIN
Synonyms
Piperacillin sodium salt ()
PIPERACILLIN ANHYDROUS ()
PIPERACILLIN SODIUM ()
(2S,5R,6R)-6-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ()
Piperacillin (sodium) ()
Sodium piperacillin ()
Pipracil ()
CL227193,Pipracil ()
Piperacillin (sodium salt) ()
NSC-757277 ()
T-1220 ()
Penmalin ()
CL-227193 ()
CL 227,193 ()
Piperacillin sodium component of zosyn ()
Pipril ()
Piperacillin (as sodium) ()
Peracin ()
Piperacillin, anhydrous ()
Piperacillin monohydrate ()
Piperacilina ()
Piperacilline ()
Piperacillin hydrate ()
Piperacillin ()
Piperacillin-d5 ()
P&D ID
PD010105
CAS
59703-84-3
61477-96-1
Tags
available
covalent binder
drug
Approved by
FDA
First approval
1981
Drug indication
infection
Bacterial infection
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Piperacillin sodium is a semisynthetic broad-spectrum ¦Â-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the ¦Â-lactamase inhibitor Tazobactam[1][2][3].
DESCRIPTION Piperacillin is a broad-spectrum semisynthetic, ampicillin-derived antibacterial. (GtoPdb)
DESCRIPTION Piperacillin is a semisynthetic broad-spectrum ¦Â-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the ¦Â-lactamase inhibitor Tazobactam[1][2][3].
DESCRIPTION Piperacillin is a penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria. (Enamine Bioactive Compounds)
Cell lines
0
Organisms
2
Compound Sets
23
Cayman Chemical Bioactives
20766
25431
ChEMBL Approved Drugs
CHEMBL1200820
CHEMBL702
ChEMBL Drugs
CHEMBL1200820
CHEMBL702
CovBinderInPDB
CBR002723
CBR002724
CBR006173
CBR006174
CBR006192
CBR006193
CBR007096
Drug Repurposing Hub
DrugBank
DB00319
DrugBank Approved Drugs
DB00319
DrugCentral
2187
DrugCentral Approved Drugs
2187
DrugMAP
DMTBKF3
DrugMAP Approved Drugs
DMTBKF3
Enamine Bioactive Compounds
EBC-12090
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS100321
Guide to Pharmacology
10921
MedChem Express Bioactive Compound Library
HY-B1286
HY-B1923
NCATS Inxight Approved Drugs
9I628532GX
NIH Clinical Collections (NCC)
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
piperacillin-sodium
External IDs
75
Properties
(calculated by RDKit )
Molecular Weight
517.16
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
1
cLogP
-0.24
TPSA
156.43
Fraction CSP3
0.48
Chiral centers
4.0
Largest ring
6.0
QED
0.34
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
intra-abdominal infections, skin infections, pelvic inflammatory disease, pneumonia
MOA
bacterial cell wall synthesis inhibitor
Target
antibiotic
Bacterial
Penicillin-binding protein (PBP)
Beta-lactamase
Therapeutic Class
Antibiotics
Pathway
Anti-infection
Source data