General
Preferred name
fluorometholone
Synonyms
Oxylone ()
Cortilet ()
Delmeson ()
Fluoromethalone ()
fluorometholone, Allergan ()
Fml-Neo ()
Fluor-Op ()
Fml Forte ()
NSC-33001 ()
Fml Fte ()
Fluaton ()
P&D ID
PD010100
CAS
426-13-1
Tags
natural product
drug
available
Approved by
FDA
First approval
1972
Drug Status
investigational
approved
Drug indication
Chronic obstructive pulmonary disease
Glucocorticoid
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Fluorometholone is a corticosteroid.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
376.2
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
0
cLogP
2.92
TPSA
74.6
Fraction CSP3
0.73
Chiral centers
8.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology&Hormones
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Target
Glucocorticoid Receptor
NR3C1
Indication
eye inflammation
MOA
Glucocorticoid Receptor agonist
Therapeutic Class
Antiallergic Agents
Source data
