General
Preferred name
ETHAMBUTOL
Synonyms
ETHAMBUTOL HYDROCHLORIDE ()
Mynah 200 ()
Ethambutol HCl ()
CL-40881 ()
Mynah 300 ()
Myambutol ()
Mynah 365 ()
Mynah 250 ()
Emb ()
Emb dihydrochloride ()
Ethambutol 2HCl ()
CL40881 ()
Ethambutol dihydrochloride ()
Ethambutol 2HCl ()
Emb (dihydrochloride) ()
Ethambutol (dihydrochloride) ()
Tibutol ()
Tambutol ()
NSC-757022 ()
Ebutol ()
Etapiam ()
Dadibutol ()
Etibi ()
Servambutol ()
Dexambutol ()
Mycobutol ()
CL 40881 ()
Ethambutoli hydrochloridum ()
Etambutol ()
Ethambutol (hydrochloride) ()
P&D ID
PD010096
CAS
1070-11-7
74-55-5
Tags
available
drug
Approved by
FDA
First approval
1967
Drug indication
Antibacterial (tuberculostatic)
Pulmonary tuberculosis
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ethambutol is used in the treatment of active tuberculosis (TB), usually in conjunction with other antituberculosis agents . The clinical formulation was originally a racemic mixture, but now contains only the active (S,S)-(+)-enantiomer. (GtoPdb)
Cell lines
0
Organisms
3
Compound Sets
23
Cayman Chemical Bioactives
23713
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL3140361
CHEMBL44884
ChEMBL Drugs
CHEMBL3140361
CHEMBL44884
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB00330
DrugBank Approved Drugs
DB00330
DrugCentral
1073
DrugCentral Approved Drugs
1073
DrugMAP
DMR87LC
DrugMAP Approved Drugs
DMR87LC
Enamine BioReference Compounds
Guide to Pharmacology
12996
MedChem Express Bioactive Compound Library
HY-B0535A
HY-B0535
NCATS Inxight Approved Drugs
8G167061QZ
NPC Screening Collection
Other bioactive compounds
Pandemic Response Box
ReFrame library
Selleckchem Bioactive Compound Library
ethambutol-hcl
TargetMol Bioactive Compound Library
T0810
The Spectrum Collection
External IDs
75
Properties
(calculated by RDKit )
Molecular Weight
204.18
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
9
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.29
TPSA
64.52
Fraction CSP3
1.0
Chiral centers
2.0
Largest ring
0.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
bacterial arabinosyltransferase inhibitor
bacterial cell wall synthesis inhibitor
Target
Arabinosyltransferase A
Antifungal
antibiotic
Bacterial
Pathway
Microbiology&virology
Anti-infection
Indication
tuberculosis
Therapeutic Class
Antitubercular Agents
Source data