General
Preferred name
OXYPHENCYCLIMINE
Synonyms
OXYPHENCYCLIMINE HYDROCHLORIDE ()
Oxyphencyclimine ()
NSC-528449 ()
Oxyphencyclimine hcl ()
Oxiphencyclimine Chloride ()
Daricon ()
P&D ID
PD010078
CAS
125-52-0
125-53-1
Tags
natural product
drug
available
Approved by
FDA
Drug Status
approved
withdrawn
Drug indication
Peptic ulcer
Max Phase
Phase 4
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Oxyphencyclimine is a synthetic anticholinergic drug with gastrointestinal antispasmodic and antisecretory action.
(GtoPdb)
DESCRIPTION
Oxyphencyclimine is a muscarinic cholinergic receptor antagonist and trade name is called as Daricon. Now it is applicated for the treatment of peptic ulcers and the relief of smooth muscle spasms in gastrointestinal.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
The hydrochloride salt form of Oxyphencyclimine which could influence the peripheral parasympathetic system and increase the stomach secretions.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
NPC Screening Collection
ReFrame library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Molecular Weight
344.21
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
1
cLogP
2.73
TPSA
62.13
Fraction CSP3
0.6
Chiral centers
1.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
A03AA01
Therapeutic Class
Anticholinergic Agents
Solubility
DMSO: ≥ 30 mg/mL
Soluble in DMSO
Source data
