General
Preferred name
PRALIDOXIME
Synonyms
PRALIDOXIME CHLORIDE ()
PRALIDOXIME MESYLATE ()
Pralidoxime ()
2-PAM chloride ()
2-Pyridinealdoxime methochloride ()
2-PAM (chloride) ()
Pralidoxime (chloride) ()
Pralidoxime (iodide) ()
PRALIDOXIME IODIDE ()
2-PAM ()
NSC-164614 ()
Protopam ()
Contrathion ()
Duodote ()
Protopam Chloride ()
Pralidoxime chloride (autoinjector) ()
Pralidoxime methanesulfonate ()
Pralidoxime methane sulphonate ()
Pralidoxime mesilate ()
Pralidoxime cation ()
Atnaa ()
Pralidoxime ion ()
Pralidoxime ()
NSC-40164 ()
NSC-7760 ()
P&D ID
PD010052
CAS
154-97-2
6735-59-7
94-63-3
51-15-0
Tags
available
drug candidate
drug
Approved by
FDA
First approval
1964
Drug Status
approved
vet_approved
Drug indication
Poisoning due to pesticides and chemicals
Cholinesterase Reactivator
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Usually available as the chloride or methiodide salts. (GtoPdb)
Compound Sets
25
Cayman Chemical Bioactives
23666
ChEMBL Approved Drugs
CHEMBL748
CHEMBL1420
ChEMBL Drugs
CHEMBL748
CHEMBL2104739
CHEMBL1420
CHEMBL14577
Concise Guide to Pharmacology 2017/18
4652
Concise Guide to Pharmacology 2019/20
4652
Concise Guide to Pharmacology 2021/22
4652
Concise Guide to Pharmacology 2023/24
4652
Drug Repurposing Hub
DrugBank
DB00733
DrugBank Approved Drugs
DB00733
DrugCentral
2231
DrugCentral Approved Drugs
2231
DrugMAP
DMGQ0ZI
DrugMAP Approved Drugs
DMGQ0ZI
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
4652
7597
MedChem Express Bioactive Compound Library
HY-B1200
HY-B1738A
NCATS Inxight Approved Drugs
P7MU9UTP52
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
pralidoxime-chloride
pralidoxime-lodide
TargetMol Bioactive Compound Library
T1111
The Spectrum Collection
External IDs
114
Properties
(calculated by RDKit )
Molecular Weight
137.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
0.32
TPSA
36.47
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.26
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Neuronal Signaling
Target
AChE
ACHE, BCHE
Cholinesterase (ChE)
AChR
MOA
AChR antagonist
Acetylcholinesterase inhibitor
Indication
organophosphate poisoning
Source data