General
Preferred name
AMPICILLIN
Synonyms
AMPICILLIN SODIUM ()
D-(-)-¦Á-Aminobenzylpenicillin ()
Aminobenzylpenicillin ()
Ampicillin acid ()
Amcill ()
D-(-)-α-Aminobenzylpenicillin ()
NCI-C56086 ()
D-(-)-??-Aminobenzylpenicillin ()
AMPICILLIN TRIHYDRATE ()
D-(-)-¦Á-Aminobenzylpenicillin (trihydrate) ()
Ampicillin (sodium) ()
Ampicillin (trihydrate) ()
D-(-)-α-Aminobenzylpenicillin (sodium salt) ()
D-(-)-α-Aminobenzylpenicillin (trihydrate) ()
D-(-)-¦Á-Aminobenzylpenicillin sodium salt ()
NCI-C56086,D-(-)-¦Á-Aminobenzylpenicillin trihydrate ()
Ampicillin (sodium salt) ()
Ampicillin sodium salt ()
Omnipen ()
Amp Equine ()
Ampicillin (as sodium) ()
Omnipen-N ()
Principen-N ()
Ampicillin sodium, sterile ()
Ampicillin sodium component of unasyn ()
NSC-755864 ()
Penbritin-S ()
Ampicillinum natricum ()
Totacillin-N ()
Polycillin-N ()
Ampicillin/ampicillin monohydrate ()
Ampicillin trihydrate ()
D-(-)-¦Á-Aminobenzylpenicillin (sodium salt) ()
Alpha-Aminobenzylpenicillin ()
AY-6108 ()
Penbritin ()
Ampicillin hydrate ()
NSC-528986 ()
Principen '500' ()
Redicilin ()
Aminobenzylpenicillin trihydrate ()
Polycillin ()
Ampicillin, anhydrous ()
Principen '125' ()
Principen '250' ()
Totacillin ()
Ultrabion ()
Pfizerpen-A ()
Britcin ()
WY 5103 ()
Semicillin ()
Principen ()
Vidopen ()
Amfipen ()
Ampicillinum ()
Ampicillin/Ampicillin Trihydrate ()
Omnipen (ampicillin) ()
P-50 ()
Poly-cillin ()
Ampilar ()
Polycillin-Prb ()
Ampicillin anhydrous ()
BRL-1341 ()
Anhydrous ampicillin ()
Ampicillin (anhydrous) ()
Tokiocillin ()
Ampicilline ()
Ampicilina ()
Probampacin ()
Ampicillin (hydrate) ()
P&D ID
PD010040
CAS
69-52-3
69-53-4
7177-48-2
33604-21-6
Tags
available
covalent binder
drug
Approved by
FDA
First approval
1965
1971
Drug indication
infection
Endocarditis
Bacterial infection
Drug Status
vet_approved
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ampicillin sodium (D-(-)-¦Á-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1].
PRICE
29
DESCRIPTION
Ampicillin Trihydrate (NCI-C56086), a broad-spectrum semisynthetic derivative of aminopenicillin, is a ??-lactam antibiotic.
DESCRIPTION
Ampicillin is a broad-spectrum, semi-synthetic, β-lactam penicillin class antibacterial. It is resistant to hydrolysis by a variety of β-lactamases, so can be to treat a diverse range of infections caused by Gram-positive and Gram-negative infections.
(GtoPdb)
PRICE
29
DESCRIPTION
Ampicillin (Aminobenzylpenicillin) is a semi-synthetic penicillin belonging to the ??-lactam group of antibiotics. Ampicillin has bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria.
DESCRIPTION
Ampicillin is a beta-lactam antibiotic that is a part of the aminopenicillin family. It is mainly used for infections and sepsis of the lungs, intestines, biliary tract, urinary tract caused by sensitive bacteria.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Ampicillin Trihydrate (NCI-C56086), a broad-spectrum semisynthetic derivative of aminopenicillin, is a β-lactam antibiotic.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic. It is used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
(Enamine Bioactive Compounds)
DESCRIPTION
Ampicillin (Aminobenzylpenicillin) is a semi-synthetic penicillin belonging to the β-lactam group of antibiotics. Ampicillin has bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
12
Compound Sets
23
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
CovBinderInPDB
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
NCATS Inxight Approved Drugs
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
100
Molecular Weight
349.11
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
1
cLogP
0.32
TPSA
112.73
Fraction CSP3
0.44
Chiral centers
4.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
PBPs
β-Lactamase
Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell
Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial
Antibacterial
Indication
respiratory tract infections, meningitis, bacterial septicemia, endocarditis, urinary tract infections, gastrointestinal infections
MOA
bacterial cell wall synthesis inhibitor
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Antibiotics
Solubility
Slightly soluble in Aqueous Acid, DMSO
Freely soluble in water
Sparingly soluble in acetone
Source data
