General
Preferred name
SECOBARBITAL
Synonyms
SECOBARBITAL SODIUM ()
Secobarbital-d5 ()
Secobarbital-d5 (CRM) ()
(rs)-secobarbital ()
Secobarbitone ()
Somatarax ()
Evronal ()
Seconal ()
Hypotrol ()
Immenox ()
Quinalbarbital ()
Secobarbital sodium free acid ()
Meballymal ()
Secobarbital cii ()
NSC-10818 ()
(rs)-secobarbital sodium ()
Seconal Sodium ()
Synate ()
Sebar ()
Immenoctal ()
Barbosec ()
Evronal sodium ()
Tuinal ()
Seconesin ()
Pramil ()
P&D ID
PD010038
CAS
76-73-3
29071-21-4
309-43-3
145243-97-6
Tags
available
drug
Approved by
FDA
First approval
1950
Drug indication
Intractable insomnia
Drug Status
vet_approved
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The approved drug is a racemic mixture of enantiomers; R-secobarbital and S-secobarbital. We show the non-stereo structure to represent the mixture.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
NPC Screening Collection
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
51
Molecular Weight
238.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
0
cLogP
1.35
TPSA
75.27
Fraction CSP3
0.58
Chiral centers
1.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N05CA06
Toxicity type
multiple
Therapeutic Class
Hypnotics and Sedatives
Source data
