General
Preferred name
HYOSCYAMINE
Synonyms
Levsin SL ()
Peptard ()
Levsinex ()
Hyoscyamine Sulphate ()
Levsinex Timecaps ()
Levsin ()
Anaspaz ()
Neoquess ()
Levsin Sulfate ()
Daturine ()
Hyoscyamine sulfate hydrate ()
L-Hyoscyamine ()
Hyoscyamine (L) ()
(-)-atropine ()
Hyoscyaminum ()
Cystospaz ()
Atropine, (s)- ()
(-)-hyoscyamine ()
Duboisine ()
(s)-(-)-hyoscyamine ()
NSC-757064 ()
Bellafoline ()
HYOSCYAMINE SULFATE ()
Egazil duretter ()
Egacene ()
Hyoscyamine sulfate dihydrate ()
Hyoscyaminum hydrobromatum ()
Daturine hbr ()
Hyoscyamine hbr ()
Daturine hydrobromide ()
HYOSCYAMINE HYDROBROMIDE ()
(?)-Hyoscyamine ()
(?)-Hyoscyamine-d3 ()
P&D ID
PD010034
CAS
620-61-1
101-31-5
Tags
available
drug
drug candidate
First approval
1869
Drug Status
approved
Max Phase
4.0
Drug indication
Anticholinergic
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
68
Properties
(calculated by RDKit )
Molecular Weight
289.17
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
1
cLogP
1.93
TPSA
49.77
Fraction CSP3
0.59
Chiral centers
4.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Target
muscarinic receptor
AChR
CHRM1, CHRM2, CHRM3, CHRM4
MOA
AChR antagonist
acetylcholine receptor antagonist
Indication
peptic ulcer disease (PUD), acute abdominal visceral spasm, ulcerative colitis, interstitial cystitis (IC), enterocolitis, irritable bowel syndrome, tremors, allergic rhinitis
Disease Area
gastroenterology, urology, neurology/psychiatry, allergy
Source data
