General
Preferred name
CEFTAZIDIME
Synonyms
GR20263 ()
Ceftazidime Pentahydrate ()
CEFTAZIDIME ANHYDROUS ()
Ceftazidime (pentahydrate) ()
Ceftazidime hydrate ()
CEFTAZIDIME SODIUM ()
GR20263 (pentahydrate) ()
Pentacef ()
NSC-759260 ()
Ceftazidime pentahydrate ()
GR 20263 ()
Fortum ()
LY 139381 ()
GR-20263 ()
J01DD07 ()
Tazicef ()
Kefazim ()
Tazidime ()
Ceftazidime (arginine formulation) ()
Fortam ()
Ceptaz ()
Fortaz ()
LY-139381 ()
P&D ID
PD010027
CAS
78439-06-2
72558-82-8
Tags
available
drug
Drug Status
approved
Drug indication
Bacterial infection
Antibacterial
Max Phase
Phase 4
First approval
1989
1985
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ceftazidime is a third generation cephalosporin bactericidal antibacterial . The clinically administered drug is the pentahydrate form.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
NCATS Inxight Approved Drugs
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
72
Properties
(calculated by RDKit )
Molecular Weight
546.1
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
3
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
2
cLogP
-1.3
TPSA
191.22
Fraction CSP3
0.32
Chiral centers
2.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
PBPs
Peptidoglycan synthase
antibiotic
Bacterial
Beta-lactamase
Anti-infection,Selection Antibiotics for Transfected Cell
MOA
Antibacterial
Antibiotic
Therapeutic Class
Antibiotics
Source data