General
Preferred name
CEFTAZIDIME
Synonyms
GR20263 ()
Ceftazidime Pentahydrate ()
CEFTAZIDIME ANHYDROUS ()
Ceftazidime hydrate ()
Ceftazidime (pentahydrate) ()
GR20263 (pentahydrate) ()
CEFTAZIDIME SODIUM ()
Tazidime ()
GR-20263 ()
LY-139381 ()
Ceftazidime component of avycaz ()
Fortaz ()
LY 139381 ()
Pentacef ()
Ceftazidime (arginine formulation) ()
NSC-759260 ()
Ceftazidime component of zavicefta ()
Tazicef ()
Fortam ()
Kefazim ()
Fortum ()
Ceftazidima ()
Ceftazidime pentahydrate ()
GR 20263 ()
Ceptaz ()
J01DD07 ()
GR 20263 MONOSODIUM SALT ()
P&D ID
PD010027
CAS
78439-06-2
72558-82-8
Tags
available
drug
Drug indication
Urinary tract infection
Bacterial infection
Drug Status
approved
Max Phase
4.0
First approval
1985
1989
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ceftazidime is a third generation cephalosporin bactericidal antibacterial . The clinically administered drug is the pentahydrate form.
(GtoPdb)
PRICE
29
DESCRIPTION
Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including ¦Â-lactamase-positive strains) and is resistant to hydrolysis by most ¦Â-lactamases[1].
DESCRIPTION
Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
NCATS Inxight Approved Drugs
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
79
Molecular Weight
546.1
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
3
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
2
cLogP
-1.3
TPSA
191.22
Fraction CSP3
0.32
Chiral centers
2.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
PBPs
Peptidoglycan synthase
Beta-lactamase
Anti-infection,Selection Antibiotics for Transfected Cell
MOA
Antibacterial
Antibiotic
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Antibiotics
Source data
