General
Preferred name
DRONABINOL
Synonyms
Marinol ()
dronabinol /
(–)-∆9-tetrahydrocannabinol ()
Δ9-Tetrahydrocannabinol solution ()
.delta.9-THC ()
.delta.9-THC-d3 (CRM) ()
Δ9-tetrahydrocannabinol ()
.delta.-9-tetrahydrocannabinol ()
ABBOTT-40566 ()
Tetrahydrocannabinols (-)-trans-.delta.9-form ()
.delta.9-tetrahydrocannabinol ()
Dronabinol component of ad313 ()
delta-9-THC ()
Dronabinol component of ad-313 ()
.delta.9-thc ()
NSC-134454 ()
J882F ()
Dronabinol component of sci-110 ()
Syndros ()
Tetrahydrocannabinol ()
QCD-84924 ()
.delta.1-thc ()
SP 104 ()
delta-9-Tetrahydrocannabinol ()
QCD 84924 ()
ABBOTT 40566 ()
SP-104 ()
(±)-?9-THC ()
(±)-?9-THC (exempt preparation) ()
?9-THC-d9 (CRM) ()
?9-THC (solution) ()
?9-THC-d3 (CRM) ()
?9-THC (Alt. Batch CRM) ()
?9-THC (CRM) ()
P&D ID
PD010009
CAS
6465-30-1
308064-99-5
1972-08-3
1363-19-5
81586-39-2
Tags
available
drug
natural product
biased GPCR ligand
Approved by
FDA
First approval
1985
Drug indication
Anorexia nervosa cachexia
Irritable bowel syndrome
Chemotherapy-induced nausea
Drug Status
approved
illicit
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Δ9-tetrahydrocannabinol is the principle active ingredient derived from the cannabis plant (Cannabis sativa). Dronabinol is the INN for the pure, synthetically produced (-)-trans-Δ9-tetrahydrocannabinol isomer of tetrahydrocannabinol (shown here).
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
8
Organisms
2
Compound Sets
19
BiasDB
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
55
Molecular Weight
314.22
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
1
cLogP
5.74
TPSA
29.46
Fraction CSP3
0.62
Chiral centers
2.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Biosynthetic Origin
Terpenoid
Therapeutic Indication
Antinauseant
Therapeutic Class
CNS & PNS
Analgesics
Source data
