General
Preferred name
DICLOXACILLIN
Synonyms
DICLOXACILLIN SODIUM ()
Dicloxacillin sodium salt hydrate ()
Varacillin ()
Lenampicillin hydrochloride ()
BRL-1702 ()
Dicloxacilline ()
Dicloxacilina ()
R-13423 ()
P&D ID
PD010001
CAS
13412-64-1
343-55-5
3116-76-5
Tags
available
drug
Approved by
FDA
First approval
1968
Drug indication
bacteriemia
Bacterial infection
Drug Status
vet_approved
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dicloxacillin is a narrow-spectrum β-lactam antimicrobial compound. (GtoPdb)
DESCRIPTION Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria. (BOC Sciences Bioactive Compounds)
Compound Sets
16
BOC Sciences Bioactive Compounds
dicloxacillin-sodium-cas-343-55-5-item-84-397788
ChEMBL Approved Drugs
CHEMBL893
ChEMBL Drugs
CHEMBL893
Drug Repurposing Hub
DrugBank
DB00485
DrugBank Approved Drugs
DB00485
DrugCentral
866
DrugCentral Approved Drugs
866
DrugMAP
DM8EU0Z
DrugMAP Approved Drugs
DM8EU0Z
Guide to Pharmacology
12261
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
COF19H7WBK
NIH Clinical Collections (NCC)
NPC Screening Collection
The Spectrum Collection
External IDs
63
Properties
(calculated by RDKit )
Molecular Weight
469.03
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
3.2
TPSA
112.74
Fraction CSP3
0.37
Chiral centers
3.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
gram-positive bacterial infections
MOA
bacterial cell wall synthesis inhibitor
Biosynthetic Origin
Peptide (beta-Lactam)
Therapeutic Indication
Antibacterial
Therapeutic Class
Antimicrobial
Antibiotics
Source data