General
Preferred name
LEVALLORPHAN
Synonyms
Levallorphan ()
Levallorphane ()
Naloxiphan ()
Levalorfano ()
Lorfan ()
Levallorphan tartrate ()
P&D ID
PD009990
CAS
152-02-3
Tags
available
drug
Approved by
FDA
Drug indication
Narcotic depression
Drug Status
approved
withdrawn
Max Phase
4.0
First approval
1982
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Levallorphan is a morphinan class opioid receptor modulator. (GtoPdb)
Cell lines
0
Organisms
2
Compound Sets
16
ChEMBL Approved Drugs
CHEMBL1254682
CHEMBL2062276
ChEMBL Drugs
CHEMBL1254682
CHEMBL2062276
Concise Guide to Pharmacology 2017/18
7209
Concise Guide to Pharmacology 2019/20
7209
Concise Guide to Pharmacology 2021/22
7209
Drug Repurposing Hub
DrugBank
DB00504
DrugBank Approved Drugs
DB00504
DrugCentral
1560
DrugCentral Approved Drugs
1560
DrugMAP
DMCOLUP
DrugMAP Approved Drugs
DMCOLUP
Guide to Pharmacology
7209
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1254682
NPC Screening Collection
Withdrawn 2.0
188
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
283.19
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
1
cLogP
3.64
TPSA
23.47
Fraction CSP3
0.58
Chiral centers
3.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
CHRNA2, OPRM1
Indication
respiratory depression
MOA
Opioid Receptor antagonist
ATC
N
Therapeutic Class
Antinarcotic Agents
Source data