General
Preferred name
cinchocaine
Synonyms
DIBUCAINE HYDROCHLORIDE ()
DIBUCAINE ()
Dibucaine (hydrochloride) ()
Cinchocaine hydrochloride ()
Dibucaine HCl ()
Cinchocaine HCl ()
Nupercaine ()
Cincaine Chloride ()
NSC-756724 ()
Heavy Solution Nupercaine ()
Nupercainal ()
NSC-159055 ()
P&D ID
PD009977
CAS
61-12-1
85-79-0
Tags
natural product
drug
available
Approved by
FDA
Drug Status
withdrawn
approved
vet_approved
Drug indication
Anaesthesia
Anesthetic (local)
Max Phase
Phase 4
First approval
1982
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Marketed formulations may contain dibucaine hydrochloride (PubChem CID 521951). (GtoPdb)
DESCRIPTION Dibucaine HCl is a local anesthetics.Among the most potent and toxic of the long-acting local anesthetics, current use of it is generally restricted to spinal and topical anesthesia. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
2
Compound Sets
23
BOC Sciences Bioactive Compounds
dibucaine-hydrochloride-cas-61-12-1-item-84-73042
Cayman Chemical Bioactives
22237
ChEMBL Approved Drugs
CHEMBL1200612
CHEMBL1086
ChEMBL Drugs
CHEMBL1200612
CHEMBL1086
Drug Repurposing Hub
DrugBank
DB00527
DrugBank Approved Drugs
DB00527
DrugCentral
859
DrugCentral Approved Drugs
859
DrugMAP
DMF9G7L
DrugMAP Approved Drugs
DMF9G7L
DrugMatrix
Guide to Pharmacology
7159
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1086
MedChem Express Bioactive Compound Library
HY-B0552A
HY-B0552
NCATS Inxight Approved Drugs
L6JW2TJG99
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
dibucaine-cinchocaine-hcl
TargetMol Bioactive Compound Library
T0364
The Spectrum Collection
Withdrawn 2.0
52
External IDs
54
Properties
(calculated by RDKit )
Molecular Weight
343.23
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
10
Ring Count
2
Aromatic Ring Count
2
cLogP
3.49
TPSA
54.46
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Target
AChR
CAM
Sodium Channel
CALM1, SCN10A, SCN5A
Indication
local anesthetic
MOA
Sodium Channel blocker
ATC
S02DA04
C05AD04
D04AB02
N01BB06
S01HA06
Therapeutic Class
Anesthetics
Source data