General
Preferred name
FOSCARNET
Synonyms
FOSCARNET SODIUM ()
Phosphonoformate ()
Foscarnet Sodium Hexahydrate ()
Foscavir ()
Foscarnet (sodium) ()
Trisodium phosphonoformate ()
Phosphonoformic acid trisodium salt ()
NSC-758148 ()
EHB 776 ()
A-29622 ()
EHB-776 ()
Foscarnet sodium hydrate ()
Foscarnet sodium hexahydrate ()
NSC-313410 ()
Foscarnet sodium anhydrous ()
Foscarnet trisodium hexahydrate ()
Dihydroxyphosphinecarboxylic Acid Oxide ()
J05AD01 ()
P&D ID
PD009975
CAS
63585-09-1
4428-95-9
34156-56-4
Tags
natural product
drug
available
Approved by
PMDA
FDA
First approval
1991
Drug Status
approved
Drug indication
Cytomegalovirus retinitis
Antiviral
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Foscarnet is an antiviral medication.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
4
Organisms
7
Compound Sets
21
CeMM library of unique drugs (CLOUD)
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
73
Molecular Weight
125.97
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.16
TPSA
94.83
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
0.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
viral DNA polymerase inhibitor
DNA polymerase inhibitor
Target
Human herpesvirus 1 DNA polymerase
Reverse Transcriptase
DNA/RNA Synthesis
Pathway
Microbiology&virology
Cell Cycle/DNA Damage
Indication
cytomegalovirus retinitis, acquired immunodeficiency syndrome (AIDS), virus herpes simplex (HSV)
Therapeutic Class
Antiviral Agents
Source data
