General
Preferred name
FOSCARNET
Synonyms
FOSCARNET SODIUM ()
Phosphonoformate ()
Sodium phosphonatoformate hexahydrate ()
Foscarnet Sodium Hexahydrate ()
Foscavir ()
Foscarnet (sodium) ()
Trisodium phosphonoformate ()
Phosphonoformic acid trisodium salt ()
Phosphonoformic acid trisodium salt hexa ()
Foscarnet trisodium hexahydrate ()
EHB 776 ()
EHB-776 ()
Foscarnet sodium hydrate ()
Foscarnet de sodio ()
Foscarnet sodium hexahydrate ()
A-29622 ()
Foscarnet sodique ()
NSC-313410 ()
NSC-758148 ()
Foscarnet sodium anhydrous ()
J05AD01 ()
Dihydroxyphosphinecarboxylic Acid Oxide ()
Sodium phosphonoformate hexahydrate ()
P&D ID
PD009975
CAS
63585-09-1
4428-95-9
34156-56-4
Tags
available
drug
Approved by
PMDA
FDA
First approval
1991
Drug indication
HIV infection
Cytomegalovirus retinitis
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Foscarnet is an antiviral medication.
(GtoPdb)
PRICE
29
DESCRIPTION
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Phosphonoformic acid is an antiviral agent. It is used in the treatment of cytomegalovirus retinitis. Phosphonoformic acid also shows activity against human herpes viruses and HIV.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
4
Organisms
6
Compound Sets
23
CeMM library of unique drugs (CLOUD)
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
76
Molecular Weight
125.97
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.16
TPSA
94.83
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
0.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
viral DNA polymerase inhibitor
DNA polymerase inhibitor
Target
Human herpesvirus 1 DNA polymerase
DNA/RNA Synthesis
Reverse Transcriptase
Virus Protease
Indication
cytomegalovirus retinitis, acquired immunodeficiency syndrome (AIDS), virus herpes simplex (HSV)
Therapeutic Class
Antiviral Agents
Pathway
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Microbiology/virology
Cell Cycle/DNA Damage
Source data
