General
Preferred name
MIVACURIUM
Synonyms
MIVACURIUM CHLORIDE ()
Mivacurium ()
Mivacurium (dichloride) ()
Mivacurium dichloride ()
BW B109OU ()
Mivacurium cation ()
Mivacurium ion ()
BW-B109OU ()
mivacurium ()
BW-1090U DICHLORIDE ()
BW B109OU DICHLORIDE ()
Mivacron ()
Chlorure de mivacurium ()
Cloruro de mivacurio ()
BWB109OU ()
BW-B109OU DICHLORIDE ()
P&D ID
PD009952
CAS
133814-19-4
106861-44-3
Tags
available
drug
drug candidate
Approved by
FDA
First approval
1992
Drug indication
Decreased liver function
Anaesthesia
Drug Status
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Mivacurium is a short-acting, nondepolarizing skeletal muscle relaxant.
(GtoPdb)
DESCRIPTION
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell[1][2][3].
DESCRIPTION
Mivacurium is a nicotinic acetylcholine receptors (nAChRs) antagonist and a non-depolarizing neuromuscular-blocking drug metabolized by plasma cholinesterase.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emergency surgical procedures of short to intermediate duration and during intubation of the trachea.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
48
Molecular Weight
1028.56
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
0
Rotatable Bonds
28
Ring Count
6
Aromatic Ring Count
4
cLogP
9.03
TPSA
144.9
Fraction CSP3
0.52
Chiral centers
4.0
Largest ring
6.0
QED
0.02
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
nAChR
ATC
M03AC10
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Therapeutic Class
Neuromuscular Nondepolarizing Agents
Source data
