General
Preferred name
BROMODIPHENHYDRAMINE
Synonyms
Bromodiphen-hydramine ()
bromazine ()
Bromodiphenhydramine ()
BROMODIPHENHYDRAMINE HYDROCHLORIDE ()
Bromodiphenhydramine (hydrochloride) ()
Ambodryl (hydrochloride) ()
Histabromamine ()
Neo-benadryl ()
Deserol ()
Bromazina ()
4-bromodiphen hydramine ()
Bromazine hydrochloride ()
Ambodryl ()
Bromodiphenhydramine hydrochloride component of bromanyl ()
NSC-36113 ()
Bromodiphenhydramine hcl ()
Bromodiphenhydramine hydrochloride component of ambenyl ()
P&D ID
PD009946
CAS
118-23-0
1808-12-4
Tags
available
drug
Approved by
FDA
First approval
1954
Drug indication
Hay fever
allergic disease
Drug Status
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Bromazine (bromodiphenhydramine) is an antihistamine. This drug also has antimicrobial action but is known to cause drowsiness. The only information regarding approval for clinical use of this drug on the US FDA website is in a drug combination with codeine. Other national approval agencies may have granted marketing authorisation.
(GtoPdb)
DESCRIPTION
Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research[1][2][3].
PRICE
58
DESCRIPTION
Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
333.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
2
cLogP
4.12
TPSA
12.47
Fraction CSP3
0.29
Chiral centers
1.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
R06AA01
Target
Bacterial
Histamine Receptor
Therapeutic Class
Antihistamines
Pathway
Anti-infection
GPCR/G protein
Immunology/Inflammation
Neuronal Signaling
Source data
