General
Preferred name
vinblastine
Synonyms
VINBLASTINE SULFATE ()
Vincaleukoblastine sulfate salt ()
NSC49842 ()
Vinblastine Sulfate Hydrate ()
Velban ()
Vincaleukoblastine sulfate (1:1) (salt) ()
Belvan, VLB ()
VLB monosulfate ()
Exal ()
Velbe ()
Vincaleucoblastine sulfate ()
Vinblastine sulfate salt ()
P&D ID
PD009913
CAS
132142-72-4
143-67-9
Tags
nuisance
natural product
drug
available
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Disrupts microtubules
(Tocris Bioactive Compound Library)
DESCRIPTION
Disrupts microtubules
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
44
Organisms
0
Compound Sets
9
Mcule NIBR MoA Box Subset
NIH Approved Oncology Drugs
NIH Mechanistic Set
Novartis Chemogenetic Library (NIBR MoA Box)
Nuisance compounds in cellular assays
ReFrame library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
45
Molecular Weight
810.42
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
3
Rotatable Bonds
7
Ring Count
9
Aromatic Ring Count
3
cLogP
3.99
TPSA
154.1
Fraction CSP3
0.59
Chiral centers
10.0
Largest ring
9.0
QED
0.18
Structural alerts
1
Tubulin modulation
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Target
nAChR
Primary Target
Microtubules
Member status
member
MOA
Tubulin disruptor
Source data
