General
Preferred name
metaraminol
Synonyms
METARAMINOL BITARTRATE ()
Metaradrine tartrate ()
Metaradrine Bitartrate ()
NSC-758425 ()
Metaraminol hydrochloride ()
Metaraminol tartrate ()
Aramine ()
Metaraminol hydrochloride, (-)- ()
Metaraminol (tartrate) ()
P&D ID
PD009893
CAS
33402-03-8
54-49-9
Tags
natural product
drug
available
Approved by
FDA
First approval
1954
Drug Status
investigational
approved
Drug indication
Adrenergic
Hypotension
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Metaraminol is the (1R,2S) stereoisomer of the racemate meta-hydroxynorephedrine (3,β-dihydroxyamphetamine; PubChem CID 4087). (GtoPdb)
Compound Sets
17
Cayman Chemical Bioactives
23938
ChEMBL Approved Drugs
CHEMBL1201319
CHEMBL2062262
ChEMBL Drugs
CHEMBL1201319
CHEMBL2062262
Drug Repurposing Hub
DrugBank
DB00610
DrugBank Approved Drugs
DB00610
DrugCentral
1721
DrugCentral Approved Drugs
1721
DrugMAP
DMWIX23
DrugMAP Approved Drugs
DMWIX23
Guide to Pharmacology
7229
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
metaraminol-bitartrate
TargetMol Bioactive Compound Library
T0279
The Spectrum Collection
External IDs
56
Properties
(calculated by RDKit )
Molecular Weight
167.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.77
TPSA
66.48
Fraction CSP3
0.33
Chiral centers
2.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
??-adrenergic receptor
¦Á-adrenergic receptor
ADRA1A
MOA
Adrenergic Receptor agonist
Indication
hypotension
Therapeutic Class
Antihypertensive Agents
Source data