General
Preferred name
DYCLONINE
Synonyms
DYCLONINE HYDROCHLORIDE ()
Dyclocaine hydrochloride ()
Dyclonine HCl ()
Dyclonine (hydrochloride) ()
dyclonine HCl, BEMA, Atrix ()
Dyclocaine HCl ()
Dyclocaine ()
Dyclone ()
NSC-23018 ()
P&D ID
PD009873
CAS
536-43-6
586-60-7
Tags
natural product
drug
available
Approved by
FDA
Drug Status
approved
withdrawn
Drug indication
Anesthetic (topical)
Pain
Max Phase
Phase 4
First approval
1982
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dyclonine is a local anesthetic.
Marketed formulations contain dyclonine hydrochloride (PubChem CID 68304). (GtoPdb)
DESCRIPTION Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
23
BOC Sciences Bioactive Compounds
dyclonine-hydrochloride-cas-536-43-6-item-84-70861
Cayman Chemical Bioactives
27667
ChEMBL Approved Drugs
CHEMBL1200478
CHEMBL1201217
ChEMBL Drugs
CHEMBL1200478
CHEMBL1201217
Drug Repurposing Hub
DrugBank
DB00645
DrugBank Approved Drugs
DB00645
DrugCentral
974
DrugCentral Approved Drugs
974
DrugMAP
DMU6OFP
DrugMAP Approved Drugs
DMU6OFP
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS101223
Guide to Pharmacology
7173
MedChem Express Bioactive Compound Library
HY-B0364A
NCATS Inxight Approved Drugs
078A24Q30O
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
dyclonine-hydrochloride
TargetMol Bioactive Compound Library
T1389
The Spectrum Collection
Withdrawn 2.0
170
External IDs
55
Properties
(calculated by RDKit )
Molecular Weight
289.2
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
1
cLogP
3.92
TPSA
29.54
Fraction CSP3
0.61
Chiral centers
0.0
Largest ring
6.0
QED
0.54
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Anti-infection
Metabolic Enzyme/Protease
Target
Sodium Channel
SCN10A, SCN5A
Aldehyde dehydrogenase (ALDH)
Bacterial
Fungal
Indication
local anesthetic
MOA
Sodium Channel blocker
ATC
R02AD04
N01BX02
Therapeutic Class
Anesthetics
Source data