General
Preferred name
flumetasone pivalate
Synonyms
Locacorten ()
NSC-107680 ()
Lorinden ()
NSC 107680 ()
NSC107680 ()
Locorten ()
flumethasone pivalate ()
Flumethasone 21-pivalate ()
Locorten-Vioform ()
P&D ID
PD009862
CAS
2002-29-1
Tags
available
drug
Approved by
FDA
Drug indication
Contact dermatitis
Drug Status
approved
Max Phase
4.0
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
76
DESCRIPTION
Flumethasone pivalate is a corticosteroid.
(GtoPdb)
DESCRIPTION
Flumethasone pivalate is a topical glucocorticoid receptor agonist with anti-inflammatory, antipruritic and vasoconstrictive properties.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Flumethasone pivalate (Locorten) has antipruritic, anti-inflammatory, and vasoconstrictive properties and can be used in studies about adrenocortical suppression, cutaneous atrophy, plasma transcortin binding, and telangiectasia.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
494.25
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
3.44
TPSA
100.9
Fraction CSP3
0.74
Chiral centers
9.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
allergic rhinitis
Target
NR3C1, SERPINA6
Glucocorticoid agonist
Glucocorticoid Receptor
MOA
Glucocorticoid Receptor agonist
Therapeutic Class
Antiinflammatory Agents
Pathway
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Source data
