General
Preferred name
Histamine Phosphate
Synonyms
Histamine (phosphate) ()
Histamine diphosphate ()
P&D ID
PD009859
CAS
51-74-1
Tags
natural product
drug
available
Drug indication
Diagnostic imaging
Drug Status
approved
Max Phase
Phase 4
First approval
1939
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Histamine phosphate is a potent histamine receptor agonist and vasodilator. It acts directly on the blood vessels to dilate arteries and capillaries mediated by both H1- and H2-receptors.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
307.03
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
8
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
-1.95
TPSA
210.22
Fraction CSP3
0.4
Chiral centers
0.0
Largest ring
5.0
QED
0.28
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Diagnostic Agents
Pathway
GPCR/G protein
Immunology/Inflammation
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Endogenous Metabolite
Histamine Receptor
Solubility
Soluble in Aqueous Acid (Slightly), Water (Slightly)
Source data
