General
Preferred name
MANNITOL
Synonyms
Mannite ()
Osmitrol ()
D-Mannitol ()
DL-Mannitol ()
Pearlitol 200 sd ()
Pearlitol 25 c ()
D-(-)-mannitol ()
E421 ()
Resectisol ()
NSC-407017 ()
Aridol Kit ()
Mannitol 300 ()
Diosmol ()
Mannitol 2080 ()
Alexitol sodium ()
Pearlitol 160 c ()
Bronchitol ()
Mannitol 35 ()
Mannitol 60 ()
Isomalt impurity, mannitol- ()
Manna Sugar ()
INS NO.421 ()
INS-421 ()
Crystalline mannitol extra-fine ()
Mannitol, d- ()
Mannitol 25 ()
Crystalline mannitol fine ()
Cordycepic acid ()
Mannogem 2080 ()
Mannitol 200 ()
Crystalline mannitol standard ()
Mannitolum ()
Pearlitol 300 dc ()
Pearlitol 50 c ()
E-421 ()
Mannitol m300 ()
P&D ID
PD009837
CAS
69-65-8
123897-58-5
133-43-7
87-78-5
Tags
available
drug
Approved by
FDA
First approval
1964
2012
Drug indication
Renal failure
Bronchiectasis
Diagnostic Aid (renal function determination)
Diuretic
Drug Status
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
15
Cayman Chemical Bioactives
23372
ChEMBL Approved Drugs
CHEMBL689
ChEMBL Drugs
CHEMBL689
Drug Repurposing Hub
DrugBank
DB00742
DrugBank Approved Drugs
DB00742
DrugCentral
935
DrugCentral Approved Drugs
935
DrugMAP
DMSCDY9
DrugMAP Approved Drugs
DMSCDY9
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-N6618
HY-N0378
ReFrame library
Selleckchem Bioactive Compound Library
D-Mannitol(Osmitrol)
dl-mannitol
TargetMol Bioactive Compound Library
T0414
External IDs
56
Properties
(calculated by RDKit )
Molecular Weight
182.08
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
6
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
-3.59
TPSA
121.38
Fraction CSP3
1.0
Chiral centers
4.0
Largest ring
0.0
QED
0.26
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Apoptosis
GPCR/G protein
Metabolic Enzyme/Protease
Neuronal Signaling
Stem Cell/Wnt
TGF-beta/Smad
Target
MDH
Adrenergic Receptor
Endogenous Metabolite
PGC-1α
PKA
Disease Area
neurology/psychiatry, ophthalmology, gastroenterology
Indication
intracranial pressure, intraocular pressure, constipation
MOA
diuretic
Therapeutic Class
Sweetening Agents
Source data