General
Preferred name
PRILOCAINE
Synonyms
PRILOCAINE HYDROCHLORIDE ()
Prilocaine HCl ()
Propitocaine hydrochloride ()
Xylonest ()
Citanest ()
Propitocaine ()
NSC 40027 ()
Prilocaine (hydrochloride) ()
L-67 ()
Citanest hydrochloride ()
NSC-758432 ()
Citanest Plain ()
L-67 HYDROCHLORIDE ()
Citanest Plain Dental ()
ASTRA 1512 ()
Prilocaina ()
ASTRA-1512 ()
Prilocaine component of emla ()
Prilocaine component of oraqix ()
Prilocaine component of fortacin ()
ASTRA-1515 ()
NSC-40027 ()
P&D ID
PD009832
CAS
1786-81-8
721-50-6
Tags
available
drug
Approved by
FDA
First approval
1965
Drug indication
Pain
Squamous cell carcinoma
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Prilocaine is often an active ingredient in fixed-mixture medications along with .
Marketed formulations may contain prilocaine hydrochloride (PubChem CID 92163). (GtoPdb)
Marketed formulations may contain prilocaine hydrochloride (PubChem CID 92163). (GtoPdb)
DESCRIPTION
Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].
PRICE
29
DESCRIPTION
Na+ channel blocker
(LOPAC library)
DESCRIPTION
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Prilocaine is a local anesthetic that is similar pharmacologically to lidocaine. It is used most often for infiltration anesthesia in dentistry.
(Enamine Bioactive Compounds)
DESCRIPTION
Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
24
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
61
Molecular Weight
220.16
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
1
cLogP
2.32
TPSA
41.13
Fraction CSP3
0.46
Chiral centers
1.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Na+/K+ ATPase
Sodium Channel
Therapeutic Class
Anesthetics
Pathway
Membrane Transporter/Ion Channel
Source data
