General
Preferred name
ETIDRONIC ACID
Synonyms
ETIDRONATE DISODIUM ()
Etidronate ()
Didronel ()
HEDP ()
HEDPA ()
Sodium etidronate ()
Etidronic acid, disodium salt ()
Etidronate (Didronel) ()
Etidronate (disodium) ()
HEDPA (disodium) ()
HEDP (disodium) ()
Etidronic acid (disodium) ()
Didronel, EHDP, Etidronic acid ()
Disodium etidronate ()
Turpinal 2nz ()
NSC-759157 ()
Didronel IV ()
Etidronic acid disodium salt ()
Didronel PMO ()
Acide etidronique ()
NSC-227995 ()
Acido etidronico ()
M05BA01 ()
Etidronate (sodium salt) ()
P&D ID
PD009821
CAS
2809-21-4
100511-44-2
187285-10-5
7414-83-7
Tags
available
drug
Approved by
FDA
First approval
1977
Drug indication
Bone Resorption Inhibitor
Paget's disease
Bone Resorption Inhibitor,Regulator (calcium)
Osteoporosis
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Etidronic acid is a bisphosphonate drug. (GtoPdb)
DESCRIPTION Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor with IC50 of 0.2 μM. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
2
Compound Sets
21
AdooQ Bioactive Compound Library
A15492
A11684
BOC Sciences Bioactive Compounds
etidronic-acid-cas-2809-21-4-89279
Cayman Chemical Bioactives
20769
ChEMBL Approved Drugs
CHEMBL1201042
CHEMBL871
ChEMBL Drugs
CHEMBL1201042
CHEMBL871
Drug Repurposing Hub
DrugBank
DB01077
DrugBank Approved Drugs
DB01077
DrugCentral
1098
DrugCentral Approved Drugs
1098
DrugMAP
DMAWJIN
DM1XHYJ
DrugMAP Approved Drugs
DMAWJIN
DM1XHYJ
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
7184
MedChem Express Bioactive Compound Library
HY-B0302A
HY-B0302
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
sodium-etidronate
etidronate-didronel
TargetMol Bioactive Compound Library
T1210
T0308
The Spectrum Collection
External IDs
61
Properties
(calculated by RDKit )
Molecular Weight
205.97
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
5
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.99
TPSA
135.29
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Proteases/Proteasome
Microbiology&virology
Apoptosis
Target
protein tyrosine phosphatase
HAP
PTPase S
V-type proton ATPase catalytic subunit
ATP6V1A, PTPRS
phosphatase
MOA
tyrosinase inhibitor
bone resorption inhibitor
Indication
Paget's disease, heterotopic ossification
Disease Area
endocrinology, orthopedics
Therapeutic Class
Bone Density Conservation Agents
Source data