General
Preferred name
OXAMNIQUINE
Synonyms
Oxamniquina ()
NSC-352888 ()
Vansil ()
Oxamniquinum ()
UK-4271 ()
UK-4261 ()
Mansil ()
P&D ID
PD009809
CAS
21738-42-1
Tags
available
drug
Approved by
FDA
First approval
1980
Drug indication
Helminthiasis
Schistosomiasis
Drug Status
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Oxamniquine is an anthelmintic with schistosomicidal activity against Schistosoma mansoni.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
NPC Screening Collection
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
279.16
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
1.81
TPSA
87.43
Fraction CSP3
0.57
Chiral centers
1.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
helminthic DNA alkylator
Target
DNA
ATC
P02BA02
Therapeutic Class
Schistosomicides
Source data
