General
Preferred name
ARBUTAMINE
Synonyms
GP 21213 ()
Arbutamine ()
ARBUTAMINE HYDROCHLORIDE ()
Arbutamina ()
GP-2-121-3 ()
Genesa ()
Arbutamine hcl ()
P&D ID
PD009807
CAS
128470-16-6
125251-66-3
Tags
available
drug
Approved by
FDA
First approval
1997
Drug indication
Cardiovascular disease
Coronary artery disease
Drug Status
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
1026
DESCRIPTION
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
ReFrame library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
317.16
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
5
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
2
cLogP
2.45
TPSA
92.95
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.38
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
β-adrenergic receptor
ATC
C01CA22
Pathway
GPCR/G protein
Neuroscience
Therapeutic Class
Cardiotonic Agents
Source data
