General
Preferred name
METHYPRYLON
Synonyms
NSC-30442 ()
Noludar ()
P&D ID
PD009804
CAS
125-64-4
Tags
natural product
drug
available
Approved by
FDA
Drug Status
illicit
approved
withdrawn
Drug indication
Insomnia
Max Phase
Phase 4
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Methyprylon is a piperidinedione derivative sedative. It is not available in the UK or US.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
183.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
0
cLogP
1.13
TPSA
46.17
Fraction CSP3
0.8
Chiral centers
1.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
ATC
N05CE02
Therapeutic Class
Sedatives and Hypnotics
Source data