General
Preferred name
MICONAZOLE
Synonyms
MICONAZOLE NITRATE ()
NSC 169434 Nitrate ()
R18134 nitrate ()
R18134 ()
Miconazole (nitrate) ()
Monistat,R18134 ()
Miconazole (nitrate) ()
R-14889 ()
NSC-169434 ()
Monistat 3 Combination Pack (Prefilled) ()
Baza cream ()
Miconazole nitrate component of easotic ()
Priconazole ()
Miconazoli nitras ()
Miconazole nitrate component of vusion ()
Acorvio ()
Monistat 1 Combination Pack ()
Monistat-Derm ()
Monistat ()
Gyno-Daktarin ()
Miconazole 7 Combination Pack ()
Dermonistat ()
Monistat 7 ()
Daktarin Aktiv ()
Monistat 7 Combination Pack ()
Miconazole 3 Combination Pack ()
Miconazole 3 ()
Monistat 3 Combination Pack ()
Miconazole 7 ()
Miconazole Nitrate Combination Pack ()
Monistat 5 ()
M-Zole 7 Dual Pack ()
Femeron ()
R 14,889 ()
M-Zole 3 Combination Pack ()
Monistat-3 Combination Pack ()
Baza cream antifungal ()
Monistat 3 ()
Conofite ()
NSC-170986 ()
Vusion ()
Dumicoat ()
Monistat-3 ()
Oravig ()
Miconazol ()
Micatin ()
Loramyc ()
Dermazole ()
Miconazole-d5 ()
P&D ID
PD009802
CAS
22832-87-7
22916-47-8
75319-48-1
1216653-50-7
Tags
available
drug
Approved by
PMDA
FDA
First approval
1974
Drug indication
infection
Fungal infection
Tinea pedis
Drug Status
vet_approved
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects[2].
PRICE 29
DESCRIPTION The approved drug miconazole is a racemic mixture of two enantiomers. The structure shown here does not specify stereochemistry and represents the mixture. (GtoPdb)
PRICE 29
DESCRIPTION Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2].
DESCRIPTION Selective inhibitor of noradrenalin transporters (Tocris Bioactive Compound Library)
DESCRIPTION Antifungal agent (Tocriscreen Plus)
DESCRIPTION Miconazole nitrate (R18134 nitrate), an imidazole antifungal agent, selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. (TargetMol Bioactive Compound Library)
DESCRIPTION Miconazole (R18134) is an imidazole antifungal agent used both topically and via intravenous infusion. (TargetMol Bioactive Compound Library)
Cell lines
6
Organisms
15
Compound Sets
30
Cayman Chemical Bioactives
15420
31175
ChEMBL Approved Drugs
CHEMBL1559
CHEMBL91
ChEMBL Drugs
CHEMBL1559
CHEMBL91
Concise Guide to Pharmacology 2017/18
2449
Concise Guide to Pharmacology 2019/20
2449
Concise Guide to Pharmacology 2021/22
2449
Concise Guide to Pharmacology 2023/24
2449
CZ-OPENSCREEN Bioactive Library
DrugBank
DB01110
DrugBank Approved Drugs
DB01110
DrugCentral
1800
DrugCentral Approved Drugs
1800
DrugMAP
DMPMYE8
DrugMAP Approved Drugs
DMPMYE8
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS101462
Guide to Pharmacology
2449
JUMP-Target 1 Compound Set
4189
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL91
MedChem Express Bioactive Compound Library
HY-B0454A
HY-B0454
NCATS Inxight Approved Drugs
7NNO0D7S5M
NIH Clinical Collections (NCC)
Pandemic Response Box
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Miconazole-nitrate
Miconazole-Monistat
TargetMol Bioactive Compound Library
T0344L
T0344
The Spectrum Collection
Tocris Bioactive Compound Library
3016
Tocriscreen Plus
3016
External IDs
64
Properties
(calculated by RDKit )
Molecular Weight
413.99
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
3
cLogP
6.45
TPSA
27.05
Fraction CSP3
0.17
Chiral centers
1.0
Largest ring
6.0
QED
0.46
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Target Type
Other Pharmacology
Pathway
Microbiology/virology
Immunology/Inflammation
Membrane Transporter/Ion Channel
Microbiology&virology
Anti-infection
Primary Target
Miscellaneous Compounds
MOA
Antifungal
Target
KCNN1
antibiotic
Bacterial
Fungal
14-α Demethylase
eNOS
Inos
Potassium Channel
Therapeutic Class
Antifungal Agents
Source data