General
Preferred name
PROFLAVINE
Synonyms
PROFLAVINE HEMISULFATE ()
ACRIFLAVINE ()
3,6-Diaminoacridine hemisulfate ()
Proflavin hemisulfate ()
3,6-Diaminoacridine ()
PROFLAVINE SULFATE ()
PROFLAVINE DIHYDROCHLORIDE ()
Proflavine sulphate ()
NSC-1510 ()
Proflavin sulfate ()
Proflavina ()
Proflavine hydrochloride ()
P&D ID
PD009793
CAS
553-30-0
1811-28-5
92-62-6
952-23-8
7459-75-8
531-73-7
Tags
available
drug candidate
drug
Approved by
FDA
Drug indication
Squamous cell carcinoma
Barrett's esophagus
Sepsis
Drug Status
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Proflavine is a topical antiseptic agent used in wound dressings to prevent infections.
(Enamine Bioactive Compounds)
DESCRIPTION
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and antiseptic purposes.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
5
Organisms
3
Compound Sets
19
AdooQ Bioactive Compound Library
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
NIH Mechanistic Set
NPC Screening Collection
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
109
Molecular Weight
209.1
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
3
cLogP
2.55
TPSA
64.93
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
F2
Anti-infection,DNA/RNA Synthesis
DNA mutation
LfrR
Potassium Channel
QacR
Thrombin
Pathway
Autophagy
DNA Damage/DNA Repair
Membrane Transporter/Ion Channel
Microbiology/virology
Proteases/Proteasome
MOA
DNA
Thrombin inhibitor
topical anesthetic
Therapeutic Class
Antiinfective Agents
Source data
