General
Preferred name
Cefapirin
Synonyms
CEPHAPIRIN SODIUM ()
CEPHAPIRIN BENZATHINE ()
Cephapirin ()
CEPHAPIRIN ()
Cefapirin Sodium ()
NSC-179171 ()
BL-P 1322 ()
Sodium Cefapirin ()
BL-P-1322 ()
Cephapirin sodium salt ()
Cefadyl ()
Metricure ()
Cefapirin benzathine ()
P&D ID
PD009785
CAS
24356-60-3
97468-37-6
21593-23-7
Tags
drug candidate
natural product
drug
available
Approved by
FDA
First approval
1974
Drug Status
withdrawn
approved
vet_approved
Drug indication
Antibacterial
Sepsis
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Cefapirin is a semisynthetic, first generation cephalosporin belonging to the β-lactam class of antibacterial compounds . (GtoPdb)
DESCRIPTION Cephalosporin C antibiotic; interferes with cell wall synthesis (LOPAC library)
Compound Sets
19
Cayman Chemical Bioactives
17406
ChEMBL Approved Drugs
CHEMBL1201043
CHEMBL1599
ChEMBL Drugs
CHEMBL1201043
CHEMBL1599
CHEMBL3989837
Drug Repurposing Hub
DrugBank
DB01139
DrugBank Approved Drugs
DB01139
DrugCentral
575
DrugCentral Approved Drugs
575
DrugMAP
DMV2JNY
DrugMAP Approved Drugs
DMV2JNY
Guide to Pharmacology
12191
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1201043
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
cephapirin-sodium
cephapirin-benzathine
TargetMol Bioactive Compound Library
T5038
T8063
The Spectrum Collection
Withdrawn 2.0
1005
External IDs
70
Properties
(calculated by RDKit )
Molecular Weight
423.06
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
1
cLogP
0.48
TPSA
125.9
Fraction CSP3
0.35
Chiral centers
2.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Cell wall synthesis
Pathway
Microbiology&virology
Target
Antibacterial
Bacterial
Antibiotics,Bacterial
Indication
mastitis
MOA
bacterial cell wall synthesis inhibitor
ATC
J01DB08
Therapeutic Class
Antibiotics
Source data