General
Preferred name
cefadroxil
Synonyms
BL-S 578 ()
CEFADROXIL ANHYDROUS ()
Cefadroxil (hydrate) ()
BL-S 578 (hydrate) ()
BL-S 578 hydrate ()
Cefadroxil hydrate ()
Cefatabs ()
Anhydrous cefadroxil ()
Cefadroxil monohydrate ()
Duracef ()
Cefadroxil (as monohydrate) ()
BL-S578 ()
Baxan ()
Cefadrops ()
Duricef ()
MJF 11567-3 ()
Cefadroxilo ()
Cefadroxil/Cefadroxil Hemihydrate ()
NSC-756664 ()
MJF-11567-3 ()
Ultracef ()
Cefadroxil-d4 (trifluoroacetate salt) ()
P&D ID
PD009784
CAS
50370-12-2
66592-87-8
Tags
available
drug
Approved by
FDA
First approval
1978
Drug indication
infection
Bacterial infection
Drug Status
vet_approved
approved
withdrawn
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
ROE Over 90% of the drug is excreted unchanged in the urine within 24 hours. Cefadroxil was detected in the placenta and breast milk.
DESCRIPTION Cefadroxil is a cephalosporin antibacterial. Like penicillin it is a β-lactam compound. (GtoPdb)
PRICE 29
DESCRIPTION Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
DESCRIPTION Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis. Cefadroxil binds to specific penicillin-binding proteins located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. (Enamine Bioactive Compounds)
DESCRIPTION Cefadroxil (BL-S 578) is a Cephalosporin Antibacterial. The chemical classification of cefadroxil anhydrous is Cephalosporins. (TargetMol Bioactive Compound Library)
Compound Sets
24
Cayman Chemical Bioactives
20365
33380
ChEMBL Approved Drugs
CHEMBL1644
ChEMBL Drugs
CHEMBL1644
Concise Guide to Pharmacology 2021/22
4831
Concise Guide to Pharmacology 2023/24
4831
Drug Repurposing Hub
DrugBank
DB01140
DrugBank Approved Drugs
DB01140
DrugCentral
526
DrugCentral Approved Drugs
526
DrugMAP
DMMC345
DrugMAP Approved Drugs
DMMC345
Enamine Bioactive Compounds
EBC-04401
Enamine BioReference Compounds
Guide to Pharmacology
4831
MedChem Express Bioactive Compound Library
HY-B1190
HY-B1190A
NCATS Inxight Approved Drugs
Q525PA8JJB
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
cefadroxil-hydrate
TargetMol Bioactive Compound Library
T0366
Withdrawn 2.0
DB01140
ZINC Tool Compounds
ZINC000003830391
External IDs
61
Properties
(calculated by RDKit )
Molecular Weight
363.09
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
1
cLogP
0.15
TPSA
132.96
Fraction CSP3
0.31
Chiral centers
3.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
PBPs
SLC15A1, SLC15A2, SLC22A6, SLC22A8
EAAT
Antibiotics,Bacterial
Disease Area
infectious disease, otolaryngology
Indication
urinary tract infections, skin infections, tonsillitis, pharyngitis
MOA
bacterial cell wall synthesis inhibitor
ATC
J01DB05
Pathway
Microbiology/virology
Anti-infection
Membrane Transporter/Ion Channel
Therapeutic Class
Antibiotics
Source data