General
Preferred name
FLAVOXATE
Synonyms
FLAVOXATE HYDROCHLORIDE ()
Flavoxato ()
DW61 ()
Rec-7-0040 ()
Flavoxate HCl ()
NSC-114649 ()
Flavoxate (hydrochloride) ()
Flavoxate ()
Urispas 200 ()
Urispas ()
DW-61 ()
Bladuril ()
Flavoxate-d5 ()
P&D ID
PD009777
CAS
3717-88-2
15301-69-6
2748541-85-5
Tags
available
drug
Approved by
FDA
First approval
1970
Drug Status
approved
Drug indication
Urgency
Nocturia
Dysuria
Suprapubic pain
Relaxant (smooth muscle)
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Marketed formulations may contain flavoxate hydrochloride (PubChem CID 441345). (GtoPdb)
DESCRIPTION Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by antagonizing muscarinic receptors. (BOC Sciences Bioactive Compounds)
Compound Sets
22
AdooQ Bioactive Compound Library
A12900
BOC Sciences Bioactive Compounds
flavoxate-hydrochloride-cas-3717-88-2-item-84-301333
Cayman Chemical Bioactives
19096
33816
ChEMBL Approved Drugs
CHEMBL1200875
CHEMBL1493
ChEMBL Drugs
CHEMBL1200875
CHEMBL1493
Drug Repurposing Hub
DrugBank
DB01148
DrugBank Approved Drugs
DB01148
DrugCentral
1175
DrugCentral Approved Drugs
1175
DrugMAP
DMKV4NL
DrugMAP Approved Drugs
DMKV4NL
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
7187
MedChem Express Bioactive Compound Library
HY-B0549A
NCATS Inxight Approved Drugs
3E74Y80MEY
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
flavoxate-hcl
TargetMol Bioactive Compound Library
T0703
External IDs
55
Properties
(calculated by RDKit )
Molecular Weight
391.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
4.41
TPSA
59.75
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.6
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
GPCR/G protein
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Target
mAChR
CHRM1, CHRM2
Calcium Channel
Phosphodiesterase (PDE)
AChR
Indication
urinary incontinence, interstitial cystitis (IC), urethritis, prostatitis
MOA
acetylcholine receptor antagonist
Therapeutic Class
Parasympatholytics
Source data