General
Preferred name
GEMIFLOXACIN
Synonyms
GEMIFLOXACIN MESYLATE ()
LB-20304a ()
SB-265805S ()
Gemifloxacin?mesylate ()
Gemifloxacin (mesylate) ()
LB 20304A ()
SB-265805-S ()
Gemifloxacin mesilate ()
Gemifloxacin methanesulfonate ()
Factive ()
Factiv ()
Gemifloxacin (mesylate) ()
P&D ID
PD009772
CAS
210353-53-0
175463-14-6
204519-65-3
Tags
natural product
drug
available
Approved by
KFDA
FDA
First approval
2003
2002
Drug Status
investigational
approved
withdrawn
Drug indication
Bacterial infection
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Gemifloxacin is a fluoroquinolone antibacterial compound with potent activity against both Gram-negative and Gram-positive microrganisms .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
48
Molecular Weight
389.15
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
2
cLogP
0.97
TPSA
123.04
Fraction CSP3
0.44
Chiral centers
1.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
DNA Damage/DNA Repair
Anti-infection
Cell Cycle/DNA Damage
Target
DNA gyrase
Topo II
antibiotic
Bacterial
DNA/RNA Synthesis
Topoisomerase
MOA
DNA gyrase inhibitor
Topoisomerase inhibitor
Therapeutic Class
Antibiotics
Source data
