General
Preferred name
PHENOBARBITAL
Synonyms
Barbexaclone ()
Phenobarbitol sodium salt ()
PHENOBARBITAL SODIUM ()
NSC-9848 ()
Eskabarb ()
Phenobarbitone ()
Solfoton ()
Talpheno ()
Phenobarbital civ ()
Luminal ()
Noptil ()
Phenylethylmalonylurea ()
NSC-128143- ()
Phenemal ()
NSC-128143 ()
Phenobarbital sod ()
Phenobarbital sodium salt ()
Sodium Phenobarbital ()
Gardenal Sod ()
Gardenal sodium ()
Phenobarbitalum natricum ()
Luminal Sodium ()
Phenobarbital-d5 (ethyl-d5) ()
Phenobarbital (CRM) ()
Phenobarbital-d5 (ethyl-d5) (CRM) ()
P&D ID
PD009761
CAS
50-06-6
11097-06-6
57-30-7
125-36-0
73738-05-3
Tags
natural product
drug
available
First approval
1912
Drug Status
investigational
approved
withdrawn
Drug indication
Anticonvulsant
Sedative-Hypnotic
Seizure disorder
Sedative-Hypnotic,Sedative-Hypnotic
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Phenobarbital is also a component of the approved drug barbexaclone (GtoPdb)
Compound Sets
17
Cayman Chemical Bioactives
20987
9001494
21353
21354
ChEMBL Approved Drugs
CHEMBL40
CHEMBL149972
ChEMBL Drugs
CHEMBL40
CHEMBL149972
DrugBank
DB01174
DrugBank Approved Drugs
DB01174
DrugCentral
2134
DrugCentral Approved Drugs
2134
DrugMAP
DMXZOCG
DrugMAP Approved Drugs
DMXZOCG
DrugMatrix
Guide to Pharmacology
2804
Ki Database
Phenobarbitol sodium salt
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL40
NPC Screening Collection
ReFrame library
The Spectrum Collection
Withdrawn 2.0
w216
External IDs
68
Properties
(calculated by RDKit )
Molecular Weight
232.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
0.7
TPSA
75.27
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N03AA02
Toxicity type
multiple
dermatological
Therapeutic Class
Anticonvulsants
Source data